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化驗
>99% (TLC)
形狀
powder
包裝
pkg of 1 × 25 mg (850697P-25mg)
製造商／商標名
Avanti Research™ - A Croda Brand 850697P
脂質類型
cardiolipins
phospholipids
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCC)=O)COC(CCCCC)=O
InChI
1S/C17H34NO8P/c1-3-5-7-9-16(19)23-13-15(26-17(20)10-8-6-4-2)14-25-27(21,22)24-12-11-18/h15H,3-14,18H2,1-2H3,(H,21,22)/t15-/m1/s1
InChI 密鑰
PELYUHWUVHDSSU-OAHLLOKOSA-N
一般說明
06:0 Phosphatidylethanolamine (PE) is a water-soluble short-chain glycero-phospholipid. It is primarily found in the inner leaflet of the plasma membrane.
Phosphatidylethanolamine (PE), an abundant phospholipid in the inner mitochondrial membrane accounts for 15–25% of the total lipid in the cells of mammals.
應用
06:0 PE (1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine/DHPE) may be used:
- as a substrate for glycerophosphoethanolamine ethanolaminephosphodiesterase (GPE-EP) in specificity assay
- as a phosphoethanolamine (PE) standard in liquid chromatographic analysis of milk phospholipids
- as a phospholipid substrate to study the kinetic parameters for the glucose transporter type 4 (Glu4) mutants
06:0 Phosphatidylethanolamine (PE) has been used as a ligand in the co-crystallization of broadly neutralizing anti-HIV antibody 4E10. It has also been used as one of the phospholipids (PLs) standards for the analysis of bovine milk PL classes by normal-phase high-performance liquid chromatography (NP-HPLC).
生化／生理作用
06:0 Phosphatidylethanolamine (PE) plays an important role in various cellular processes such as autophagy, cell division and protein folding. In addition it also acts as a precursor for the synthesis of several protein modifications and as an intermediate in the synthesis of other glycerophospholipids.
Phosphoethanolamine (PE) serves as a precursor in membrane phospholipid biosynthesis. Phosphatidylethanolamine controls membrane fluidity in eukaryotic cells.
包裝
5 mL Clear Glass Sealed Ampule (850697P-25mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
Crystallographic identification of lipid as an integral component of the epitope of HIV broadly neutralizing antibody 4E10
Irimia A, et al.
Immunity, 44(1), 21-31 (2016)
Liquid chromatographic analysis of milk phospholipids with on-line pre-concentration
Fagan P, et al.
Journal of Chromatography A, 1054(1-2), 241-249 (2004)
Peter Fagan et al.
Journal of chromatography. A, 1054(1-2), 241-249 (2004-11-24)
Two methods have been developed for the analysis of bovine milk phospholipid (PL) classes by NP-HPLC with evaporative light scattering detection. In the first method, a PVA-Sil guard column was used for the rapid determination of the major milk PL
Rosie Dawaliby et al.
The Journal of biological chemistry, 291(7), 3658-3667 (2015-12-15)
Adequate membrane fluidity is required for a variety of key cellular processes and in particular for proper function of membrane proteins. In most eukaryotic cells, membrane fluidity is known to be regulated by fatty acid desaturation and cholesterol, although some
Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei
Farine L, et al.
Scientific reports, 5, 16787-16787 (2015)
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