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化驗
>99% (TLC)
形狀
liquid
包裝
pkg of 1 × 2.5 mL (850340C-25mg)
製造商／商標名
Avanti Research™ - A Croda Brand 850340C
濃度
10 mg/mL (850340C-25mg)
脂質類型
phospholipids
cardiolipins
運輸包裝
dry ice
儲存溫度
−20°C
一般說明
13:0 PC is ditridecanoyl phosphatidyl choline (DTPC). Phosphatidylcholine (PC) is a phospholipid, present in endothelial cells, corneal epithelial cells, and fibroblast. Structurally, PC has a polar head consisting of choline and phosphate and two non-polar tails consisting of fatty acids. The polar head group is water soluble and the non-polar tails are water insoluble. Due to its amphiphilic properties, it is present in the cell membrane. In the human body, liver synthesizes PC. Dietary sources of PC are egg and soybeans.
Phosphatidylcholine (PC), a phospholipid carries a positively charged quaternary amine and a negatively charged phosphate in its headgroup. It can form strong bilayer and is an important component of mammalian membranes.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
應用
13:0 PC (1,2-ditridecanoyl-sn-glycero-3-phosphocholine) may be used as a lipid standard for the quantification of phosphatidylcholines (PCs) by mass spectrometric analysis.
13:0 Phosphatidylcholine (PC) has been used as a lipid standard for mass spectrometry.
生化／生理作用
Phosphatidylcholine (PC) is the precursor for the triacylglycerol synthesis. The concentration of PC decreases owing to enhanced triacylglycerol production in the liver. Phosphatidylcholine may be a biomarker for the diagnosis of fatty liver. Its structure enables them to be used in food industry as emulsifiers.
Phosphatidylcholine (PC) can serve as a surfactant in the mucus.
包裝
5 mL Clear Glass Sealed Ampule (850340C-25mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
訊號詞
Danger
危險分類
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
標靶器官
Central nervous system, Liver,Kidney
水污染物質分類（WGK）
WGK 3
Phospholipid makeup of the breast adipose tissue is impacted by obesity and mammary cancer in the mouse: Results of a pilot study
Margolis M, et al.
Biochimie, 108(11), 133-139 (2015)
Genea Edwards et al.
Biochimie, 101, 232-247 (2014-02-25)
To compare phospholipid (phosphatidylcholine, phosphatidylserine, phosphatidylethanolamine and phosphatidylinositol) profiles of human control and glaucomatous aqueous humor (AQH). AQH samples were procured during surgery from human POAG and control subjects (n = 15 each). Samples were used following institutional review board
Self-assembled phospholipid unilamellar vesicles
Liposomes, Part G (2009)
Mass spectrometric analyses of phosphatidylcholines in alkali-exposed corneal tissue
Crane AM, et al.
Investigative Ophthalmology & Visual Science, 53(11), 7122-7130 (2012)
Altered plasma lipidome profile of dairy cows with fatty liver disease
Gerspach C, et al.
Research in Veterinary Science, 110, 47-59 (2017)
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