描述
1,2-dilauroyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt)
化驗
>99% (TLC)
形狀
powder
包裝
pkg of 1 × 200 mg (840435P-200mg)
pkg of 1 × 25 mg (840435P-25mg)
製造商/商標名
Avanti Research™ - A Croda Brand
脂質類型
cardiolipins
phospholipids
運輸包裝
dry ice
儲存溫度
−20°C
InChI
1S/C30H59O10P.Na/c1-3-5-7-9-11-13-15-17-19-21-29(33)37-25-28(26-39-41(35,36)38-24-27(32)23-31)40-30(34)22-20-18-16-14-12-10-8-6-4-2;/h27-28,31-32H,3-26H2,1-2H3,(H,35,36);/q;+1/p-1/t27?,28-;/m1./s1
InChI 密鑰
CIRSYGHBBDDURM-AMRYRHMLSA-M
一般說明
Phosphatidylglycerol (PG) is one of the most important lipid, found in Gram-positive bacteria. It has odd-numbered branched-chain fatty acids as acyl chains. This phospholipid is ubiquitously present in the membranes of several organisms. 12:0 PG (1,2-dilauroyl-sn-glycero-3-phospho-(1′-rac-glycerol)/DLPG) is an anionic phospholipid. It is an anionic analogue of the zwitterionic phospholipid, dilauroyl phosphatidylcholine (DLPC).
應用
12:0 PG (1,2-dilauroyl-sn-glycero-3-phospho-(1′-rac-glycerol)) has been used in monomolecular films as representative lipid component of eukaryotic membranes to study the generality of the non-steroidal anti-inflammatory drug (NSAID)-related effect. It may also be used:
- in the preparation of liposomes for PagP folding assays
- as a component in pyrene labeleld liposomes
- to construct liposome/lipid vesicle
生化/生理作用
Phosphatidylglycerol (PG) is known to participate in photosynthesis.
包裝
5 mL Amber Glass Screw Cap Vial (840435P-200mg)
5 mL Amber Glass Screw Cap Vial (840435P-25mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
Biochimica et biophysica acta, 1778(12), 2710-2716 (2008-08-19)
There is mounting evidence that the lipid matrix of neuronal cell membranes plays an important role in the accumulation of beta-amyloid peptides into senile plaques, one of the hallmarks of Alzheimer's disease (AD). With the aim to clarify the molecular
The Journal of biological chemistry, 288(28), 20162-20172 (2013-06-06)
Antimicrobial or host defense peptides are innate immune regulators found in all multicellular organisms. Many of them fold into membrane-bound α-helices and function by causing cell wall disruption in microorganisms. Herein we probe the possibility and functional implications of antimicrobial
FATS vert Occurrence
Encyclopedia of food sciences and nutrition, 2293-2296 (2003)
Biochimica et biophysica acta. Biomembranes, 1862(2), 183135-183135 (2019-11-19)
The mechanism of action of the anti-Listeria peptide enterocin CRL35 was studied with biophysical tools by using lipid mixtures that mimicked Gram-positive plasma membranes. Langmuir monolayers and infrared spectroscopy indicated that the peptide readily interacted with phospholipid assembled in monolayers
ACS nano, 14(2), 1609-1622 (2019-12-04)
Antimicrobial resistance stimulates the search for antimicrobial forms that may be less subject to acquired resistance. Here we report a conceptual design of protein pseudocapsids exhibiting a broad spectrum of antimicrobial activities. Unlike conventional antibiotics, these agents are effective against
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