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化驗
>99% (TLC)
形狀
liquid
包裝
pkg of 1 × 1 mL (810298C-1mg)
製造商／商標名
Avanti Research™ - A Croda Brand 810298C
濃度
1 mg/mL (810298C-1mg)
運輸包裝
dry ice
儲存溫度
−20°C
一般說明
Lipid droplets (LDs) are organelles that store lipids as reservoirs of metabolic energy and membrane lipid precursors, and they have been identified in the nucleus of some cells. LDs can be found in most eukaryotic cells. Most prominent are LDs in adipocytes, which make up most of the cellular volume, but other metabolically active cell types, such as liver or muscle cells, also have abundant LDs. LDs are unusual organelles in that they are bound by a monolayer of surface phospholipids, into which specific proteins are embedded, such as perilipins and metabolic enzymes. The cell biology of LDs as cellular organelles is only beginning to be unraveled. Avanti now offers a series of fluorescently-labeled mono-, di-, and triglycerides, which are useful for studying these important cellular organelles.
應用
18:1-18:1-C11TopFluor™ TG (1,2-dioleoyl-3-[11-(dipyrrometheneboron difluoride)undecanoyl]-sn-glycerol) has been used as a standard to validate fluorescent lipid bands in fatty acid incorporation assay. It may also be used in fluorescent lipid synthesis.
包裝
5 mL Clear Glass Sealed Ampule (810298C-1mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
訊號詞
Danger
危險分類
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
標靶器官
Central nervous system, Liver,Kidney
水污染物質分類（WGK）
WGK 3
Øystein Sæle et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1863(9), 948-957 (2018-05-21)
The zebrafish larva is a powerful tool for the study of dietary triglyceride (TG) digestion and how fatty acids (FA) derived from dietary lipids are absorbed, metabolized and distributed to the body. While fluorescent FA analogues have enabled visualization of
Hanaa Hariri et al.
The Journal of cell biology, 218(4), 1319-1334 (2019-02-28)
Lipid droplets (LDs) serve as cytoplasmic reservoirs for energy-rich fatty acids (FAs) stored in the form of triacylglycerides (TAGs). During nutrient stress, yeast LDs cluster adjacent to the vacuole/lysosome, but how this LD accumulation is coordinated remains poorly understood. The
Robert V Farese et al.
The Journal of cell biology, 212(1), 7-8 (2016-01-06)
Lipid droplets (LDs) are sometimes found in the nucleus of some cells. In this issue, Ohsaki et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201507122) show that the nuclear membrane, promyelocytic leukemia bodies, and the protein PML-II play a role in nuclear
Nora Kory et al.
Trends in cell biology, 26(7), 535-546 (2016-03-21)
How proteins specifically localize to the phospholipid monolayer surface of lipid droplets (LDs) is being unraveled. We review here the major known pathways of protein targeting to LDs and suggest a classification framework based on the localization origin for the
Nora Kory et al.
Developmental cell, 34(3), 351-363 (2015-07-28)
Lipid droplets (LDs) are lipid storage organelles that grow or shrink, depending on the availability of metabolic energy. Proteins recruited to LDs mediate many metabolic functions, including phosphatidylcholine and triglyceride synthesis. How the LD protein composition is tuned to the supply
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