跳转至内容
Merck
所有图片(3)

Key Documents

810250C

Avanti

25-NBD 胆固醇

Avanti Research - A Croda Brand 810250C

别名:

25-[N-[(7-硝基-2-1,3-苯并恶二唑-4-基)甲基]氨基]-27-降胆甾醇

登录查看公司和协议定价


About This Item

经验公式(希尔记法):
C33H48N4O4
分子量:
564.76
分類程式碼代碼:
12352211
NACRES:
NA.25

化驗

>99% (TLC)

形狀

liquid

包裝

pkg of 1 × 1 mL (810250C-10mg)
pkg of 1 × 1 mL (810250C-1mg)
pkg of 1 × 1 mL (810250C-5mg)

製造商/商標名

Avanti Research - A Croda Brand 810250C

濃度

1 mg/mL (810250C-1mg)
10 mg/mL (810250C-10mg)
5 mg/mL (810250C-5mg)

運輸包裝

dry ice

儲存溫度

−20°C

InChI

1S/C33H48N4O4/c1-20(7-6-8-21(2)36(5)28-13-14-29(37(39)40)31-30(28)34-41-35-31)25-11-12-26-24-10-9-22-19-23(38)15-17-32(22,3)27(24)16-18-33(25,26)4/h9,13-14,20-21,23-27,38H,6-8,10-12,15-19H2,1-5H3/t20-,21?,23+,24+,25+,26+,27+,32+,33-/m1/s1

InChI 密鑰

RMGLSQAGXRZCPZ-OVHOIDCTSA-N

一般說明

25-NBD胆固醇是胆固醇的荧光衍生物。其荧光特性是由于存在NBD(2-(4-硝基-2,1,3-苯并恶二唑-7-基)氨乙基)基团。

應用

25-NBD胆固醇可用作共聚焦显微镜的标记物,用于研究内体运输和囊泡形成。

生化/生理作用

胆固醇通过一系列酶促反应(称为甲羟戊酸途径)合成。胆固醇在质膜的结构和稳定性中起主要作用,并且还参与胆钙化醇(维生素D3)的合成。胆固醇在血管壁或动脉上聚积会导致血流阻塞,导致严重疾病动脉硬化。它是胆汁酸和类固醇激素(如孕酮、睾酮、皮质醇和醛固酮)合成的前体。

包裝

5 mL透明玻璃密封安瓿 (810250C-10mg)
5 mL透明玻璃密封安瓿 (810250C-1mg)
5 mL透明玻璃密封安瓿 (810250C-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

標靶器官

Liver,Kidney, Respiratory system

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

does not flash

閃點(°C)

does not flash


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Anita H Payne et al.
Endocrine reviews, 25(6), 947-970 (2004-12-08)
Significant advances have taken place in our knowledge of the enzymes involved in steroid hormone biosynthesis since the last comprehensive review in 1988. Major developments include the cloning, identification, and characterization of multiple isoforms of 3beta-hydroxysteroid dehydrogenase, which play a
Johan Tornmalm et al.
Scientific reports, 9(1), 18133-18133 (2019-12-04)
Protein-lipid interactions in cellular membranes modulate central cellular functions, are often transient in character, but occur too intermittently to be readily observable. We introduce transient state imaging (TRAST), combining sensitive fluorescence detection of fluorophore markers with monitoring of their dark
Santiago Lima et al.
The Journal of biological chemistry, 292(8), 3074-3088 (2017-01-05)
The balance between cholesterol and sphingolipids within the plasma membrane has long been implicated in endocytic membrane trafficking. However, in contrast to cholesterol functions, little is still known about the roles of sphingolipids and their metabolites. Perturbing the cholesterol/sphingomyelin balance

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门