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化驗
>99% (TLC)
形狀
powder
包裝
pkg of 1 × 1 mg (810226P-1MG)
pkg of 1 × 250 μg (810226P-250ug)
製造商／商標名
Avanti Research™ - A Croda Brand 810226P
運輸包裝
dry ice
儲存溫度
−20°C
一般說明
C6-NBD Lactosyl ceramide is a commercially available fluorescent analog of compound lactosyl ceramide. Lactosyl ceramide is present on neutrophils and macrophages.
應用
C6-NBD Lactosyl Ceramide has been used in:
- lactosylceramide synthase assay as a fluorescent acceptor substrate identified using fluorescence based detector in HPLC(1)
- phospholipid labeling and fluorescence-lifetime imaging microscopy (FILM) of cell membranes(6)
生化／生理作用
Lactosyl ceramide is utilized for synthesis of various glycosphingolipids like oligoglycosylceramides and gangliosides in vertebrates. It is an important molecule involved in signaling cascades leading to phenotypic changes such as adhesion, migration, cell proliferation and angiogenesis.
包裝
5 mL Amber Glass Screw Cap Vial (810226P-1MG)
5 mL Amber Glass Screw Cap Vial (810226P-250ug)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
W I Weis et al.
Annual review of biochemistry, 65, 441-473 (1996-01-01)
Lectins are responsible for cell surface sugar recognition in bacteria, animals, and plants. Examples include bacterial toxins; animal receptors that mediate cell-cell interactions, uptake of glycoconjugates, and pathogen neutralization; and plant toxins and mitogens. The structural basis for selective sugar
S Hakomori et al.
Journal of biochemistry, 118(6), 1091-1103 (1995-12-01)
Glycosphingolipids (GSLs), cell type-specific markers which change dramatically during ontogenesis and oncogenesis, have been implicated as playing major roles in cellular interactions and control of cell proliferation in multicellular organisms. These functional roles have been partially clarified through two types
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