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Merck

W332208

Sigma-Aldrich

硫胺 盐酸盐

≥98%, FCC, FG

别名:

硫胺素 盐酸盐, 维生素 B 1 盐酸盐

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About This Item

经验公式(希尔记法):
C12H17ClN4OS · HCl
CAS号:
分子量:
337.27
FEMA號碼:
3322
Beilstein:
3851771
EC號碼:
歐洲委員會號碼:
4226
MDL號碼:
分類程式碼代碼:
12164502
PubChem物質ID:
Flavis號碼:
16.027
NACRES:
NA.21

生物源

synthetic

品質等級

等級

FG
Halal
Kosher

agency

meets purity specifications of JECFA

法律遵循

EU Regulation 1334/2008 & 872/2012
FCC

化驗

≥98%

形狀

powder or crystals

顏色

white to yellow-white

mp

250 °C (dec.) (lit.)

溶解度

H2O: 1 g/10 mL, clear, colorless

應用

flavors and fragrances

文件

see Safety & Documentation for available documents

食物過敏原

no known allergens

感官的

sour

SMILES 字串

CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]

InChI

1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1

InChI 密鑰

DPJRMOMPQZCRJU-UHFFFAOYSA-M

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一般說明

Thiamine hydrochloride is a water-soluble vitamin generally used as a nutrient supplement. When it undergoes heat-degradation, it may form volatile flavor compounds such as hydrogen sulfide, 2-methylthiopehene, 2-methylfuran, and 4,5-dihydro-2-methylthiophene.

應用


  • Construction of hyaluronic acid-functionalized magnolol nanoparticles for ulcerative colitis treatment.: This innovative study explores the synthesis of nanoparticle systems using hyaluronic acid-functionalized magnolol, highlighting thiamine hydrochloride′s role in enhancing therapeutic efficacy and stability in gastrointestinal treatments. This research underlines the biochemical application of thiamine hydrochloride in developing advanced drug delivery systems (Li Y et al., 2024).

  • Constructing Highly Stable Zinc Metal Anodes via Induced Zn(002) Growth.: Investigates the electrochemical stability of zinc anodes, with thiamine hydrochloride playing a critical role in modulating the electrochemical properties and enhancing the anode′s performance, showcasing its potential in next-generation battery technologies (Hu S et al., 2024).

  • Subclinical thiamine deficiency results in failed reproduction in Arctic foxes.: This study identifies the pivotal role of thiamine hydrochloride in preventing reproductive failures linked to nutritional deficiencies in wildlife, extending its application beyond human health to include environmental and conservation aspects (Jackson C et al., 2024).

  • Density Functional Theory and Density Functional Tight Binding Studies of Thiamine Hydrochloride Hydrates.: Highlights computational studies on the molecular structure and stability of thiamine hydrochloride, providing crucial insights into its physicochemical properties and interactions at the molecular level, critical for pharmaceutical formulations (Napiórkowska E et al., 2023).

  • Effects of Nutrients on the Growth of and Free Exopolysaccharide Biosynthesis by Streptococcus thermophilus 937 in a Chemically Defined Medium.: Examines the influence of thiamine hydrochloride among other nutrients on the microbial synthesis processes, underlining its essential role in microbial nutrition and metabolic engineering (Wa Y et al., 2023).

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

Lot/Batch Number

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访问文档库

Validation of HPLC method for determination of thiamine hydrochloride, riboflavin, nicotinamide, and pyridoxine hydrochloride in syrup preparation
Yantih N, et al.
Canadian Journal on Scientific and Industrial Research, 2(7), 269-278 (2011)
Encyclopedia of Food and Color Additives, 1, 2777-2777 null
Spectrophotometric determination of ascorbic acid and thiamine hydrochloride in pharmaceutical products using derivative spectrophotometry
Abdel-Hamid ME, et al.
Analyst, 110(7), 831-835 (1985)
Volatile flavor compounds produced by heat degradation of thiamine (vitamin B1).
Arnold RG, et al.
Journal of Agricultural and Food Chemistry, 17(2), 390-392 (1969)
High-performance liquid chromatography method for the simultaneous determination of thiamine hydrochloride, pyridoxine hydrochloride and cyanocobalamin in pharmaceutical formulations using coulometric electrochemical and ultraviolet detection
Marszall LM, et al.
Journal of Chromatography A, 1094(1-2), 91-98 (2005)

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