QBD10867

SPDP-dPEG^®₃₆-NHS ester

>95% (HPLC)

• 别名: OPSS-PEG₁₅₀₀-NHS ester, OPSS-PEG₃₆-NHS ester, SPDP-PEG-NHS ester, SPDP-PEG₃₆-NHS ester
• 经验公式（希尔记法）: C₈₇H₁₆₁N₃O₄₁S₂
• 分子量: 1969.33
• MDL號碼: MFCD21363283
• 分類程式碼代碼: 12352108
• NACRES: NA.22

属性

• 化驗: >95% (HPLC)
• 形狀: solid or viscous liquid
• 反應適用性: reaction type: Pegylations
• 聚合物結構: shape: linear; functionality: heterobifunctional
• 運輸包裝: ambient
• 儲存溫度: −20°C

说明

特點和優勢

SPDP-dPEG₃₆-NHS ester is an amphiphilic, water-soluble PEGylation reagent that is designed to crosslink amines and free thiols. SPDP (also referred to as orthopyridyl disulfide, or OPSS) reacts with sulfhydryl groups to form disulfide bonds. The N-hydroxysuccinimidyl (NHS) ester reacts with free amines to form amide bonds. The single molecular weight, discrete chain length polyethylene glycol (dPEG) chain is 115 atoms (137.8 Å) long. SPDP-dPEG36-NHS ester is used like SPDP and its related hydrophobic products. However, the water-soluble dPEG product prevents hydrophobicity-triggered precipitation of compounds to which it is conjugated. SPDP-dPEG₃₆-NHS ester is a monodisperse equivalent of the polymeric PEG₁₅₀₀.

法律資訊

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable