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Merck

QBD10109

Sigma-Aldrich

Acid-dPEG®5-NHS ester

别名:

Polyethylene glycol

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About This Item

经验公式(希尔记法):
C18H29NO11
分子量:
435.42
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.22

化驗

>90%

形狀

solid or viscous liquid

反應適用性

reagent type: cross-linking reagent
reactivity: amine reactive

官能基

NHS ester
carboxylic acid

聚合物結構

shape: linear
functionality: heterobifunctional

運輸包裝

ambient

儲存溫度

−20°C

SMILES 字串

OC(CCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)=O

特點和優勢

Acid-dPEG®5-NHS ester allows conjugation to two different moieties, each containing free amines. Because the single molecular weight dPEG® spacers contain an N-hydroxysuccinimide ester only on one end of the spacer, greater control of the conjugation reaction can be maintained. The free acid end of the spacer can be left unreacted to modify the surface properties of the molecule to which it is conjugated, or the free acid end can be activated and conjugated to a different group at a later time. The dPEG® spacers provide precise spacing/distance control, and the dPEG® itself provides the well-known benefits of increased water solubility; decreased immunogenicity; protection from proteolysis; increased hydrodynamic volume; and increased serum half-life.

法律資訊

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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