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Merck

QBD10525

Sigma-Aldrich

Azido-dPEG®23-amine

别名:

Polyethylene glycol

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About This Item

经验公式(希尔记法):
C48H98N4O23
分子量:
1099.30
MDL號碼:
分類程式碼代碼:
12352116
PubChem物質ID:
NACRES:
NA.22

化驗

>90%

形狀

solid or viscous liquid

反應適用性

reaction type: click chemistry
reagent type: cross-linking reagent
reaction type: click chemistry

聚合物結構

shape: linear
functionality: heterobifunctional

運輸包裝

ambient

儲存溫度

−20°C

SMILES 字串

NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

一般說明

Azido-dPEG®23-amine is a biocompatible crosslinking reagent used in copper(I)/ruthenium catalyzed, and strain-promoted click chemistry reactions.

特點和優勢

The azido-dPEG®23-amine contains an azide function on one end of a single molecular weight dPEG® spacer (86.8 Å) and a reactive group on the other end of the spacer. The dPEG® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The primary amine reacts with acids and active esters. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

法律資訊

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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