QBD10501

Azido-dPEG^®₄-NHS ester

• 别名: 3-(Azidotetra(ethyleneoxy))propionic acid succinimidyl ester, NHS-Peg4-Azide, Polyethylene glycol
• 经验公式（希尔记法）: C₁₅H₂₄N₄O₈
• CAS号: 944251-24-5
• 分子量: 388.37
• MDL號碼: MFCD13184948
• 分類程式碼代碼: 12352108
• PubChem物質ID: 329823930
• NACRES: NA.22

属性

• 化驗: >90%
• 形狀: solid or viscous liquid
• 反應適用性: reaction type: click chemistry; reagent type: cross-linking reagent; reaction type: click chemistry
• 官能基: NHS ester; azide
• 聚合物結構: shape: linear; functionality: heterobifunctional
• 運輸包裝: ambient
• 儲存溫度: −20°C
• SMILES 字串: O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCN=[N+]=[N-]
• InChI: 1S/C15H24N4O8/c16-18-17-4-6-24-8-10-26-12-11-25-9-7-23-5-3-15(22)27-19-13(20)1-2-14(19)21/h1-12H2
• InChI 密鑰: OIGKWPIMJCPGGD-UHFFFAOYSA-N

说明

特點和優勢

The azido-dPEG^®₄-NHS ester contains an azide function on one end of a single molecular weight dPEG^® spacer (17.7 Å) and a reactive group on the other end of the spacer. The dPEG^® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. NHS ester readily reacts with amines in aqueous solution or organic solvent. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

法律資訊

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable