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Merck
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文件

D87201

Sigma-Aldrich

2-二乙氨基氯乙烷 盐酸盐

99%

别名:

2-(二乙基氨基)乙基氯 盐酸盐, 2-氯代三乙胺 盐酸盐

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About This Item

线性分子式:
(C2H5)2NCH2CH2Cl · HCl
CAS号:
869-24-9
分子量:
172.10
Beilstein:
3591991
EC號碼:
212-786-4
MDL號碼:
MFCD00012519
分類程式碼代碼:
12352100
PubChem物質ID:
24894220
NACRES:
NA.22

化驗

99%

形狀

crystals

mp

208-210 °C (lit.)

SMILES 字串

Cl.CCN(CC)CCCl

InChI

1S/C6H14ClN.ClH/c1-3-8(4-2)6-5-7;/h3-6H2,1-2H3;1H

InChI 密鑰

RAGSWDIQBBZLLL-UHFFFAOYSA-N

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應用

2-Chloro-N,N-diethylethylamine hydrochloride can be used as an alkylating reagent for the synthesis of:
  • Substituted oxindole derivatives to be used as growth hormone secretagogs.
  • 1-Substituted-5,6-dinitrobenzimidazoles with antimicrobial and antiprotozoal activities.
  • Thiophene containing triarylmethane (TRAM) derivatives to be used as antitubercular agents.
  • Tris(2-(diethylamino)ethyl)amine to be used as a catalyst in combination with CuBr (Et6TREN/CuBr) for atom transfer radical polymerization of n-butyl acrylate.

It can also be used for the derivatization of chitosan to incorporate aminofunctionality onto it at C-6 position.

訊號詞

Danger

危險分類

Acute Tox. 2 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Muta. 2 - Skin Corr. 1B

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges

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Thiophene containing triarylmethanes as antitubercular agents.
Parai MK, et al.
Bioorganic & Medicinal Chemistry Letters, 18(1), 289-292 (2008)
Reactive oxygen species scavenging activity of aminoderivatized chitosan with different degree of deacetylation.
Je JY, et al.
Bioorganic & Medicinal Chemistry, 14(17), 5989-5994 (2006)
New amine-based tripodal copper catalysts for atom transfer radical polymerization.
Inoue Y and Matyjaszewski K
Macromolecules, 37(11), 4014-4021 (2004)
Zygmunt Kazimierczuk et al.
Acta biochimica Polonica, 49(1), 185-195 (2002-07-26)
Two series of benzimidazole derivatives were sythesised. The first one was based on 5,6-dinitrobenzimidazole, the second one comprises 2-thioalkyl- and thioaryl-substituted modified benzimidazoles. Antibacterial and antiprotozoal activity of the newly obtained compounds was studied. Some thioalkyl derivatives showed remarkable activity
Oxindole derivatives as orally active potent growth hormone secretagogues.
Tokunaga T, et al.
Journal of medicinal chemistry, 44(26), 4641-4649 (2001)
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