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C8601

Sigma-Aldrich

Z-Pro-OH

99%

别名:

Z-L-脯氨酸

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About This Item

经验公式（希尔记法）:
C13H15NO4
CAS号:
1148-11-4
分子量:
249.26
Beilstein:
88579
EC號碼:
214-557-4
MDL號碼:
MFCD00003170
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
24893080
NACRES:
NA.22

化驗

99%

形狀

powder or crystals

光學活性

[α]20/D −42°, c = 2 in ethanol

反應適用性

reaction type: solution phase peptide synthesis

技術

NMR: suitable

顏色

white

mp

76-78 °C (lit.)

應用

peptide synthesis

SMILES 字串

OC(=O)[C@@H]1CCCN1C(=O)OCc2ccccc2

InChI

1S/C13H15NO4/c15-12(16)11-7-4-8-14(11)13(17)18-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,15,16)/t11-/m0/s1

InChI 密鑰

JXGVXCZADZNAMJ-NSHDSACASA-N

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相关类别

應用

Z-Pro-OH can be used:
  • As a starting material to prepare aib-pro endothiopeptides of pharmacological importance.
  • To prepare biologically significant fluorophore-labeled peptide tetramers or dimers.
  • As a reactant to synthesize benzoxazole derived human neutrophil elastase (HNE) inhibitors.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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分析证书(COA)

Lot/Batch Number
BCCC6213
BCCB4986
BCBT8771
BCBQ3200V
BCBL5532V

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A new dendrimer scaffold for preparing dimers or tetramers of biologically active molecules
Raju N, et al.
Tetrahedron Letters, 46(9), 1463-1465 (2005)
Design and synthesis of peptide-based carboxylic acid-containing transition-state inhibitors of human neutrophil elastase
Sato F, et al.
Bioorganic & medicinal chemistry letters, 12(4), 551-555 (2002)
Cytotoxicity of carbobenzoxy-protected amino acids.
M Dolenga et al.
In vitro cellular & developmental biology : journal of the Tissue Culture Association, 28A(5), 300-302 (1992-05-01)
Anna Lupi et al.
Biochimica et biophysica acta, 1744(2), 157-163 (2005-05-10)
Prolidase deficiency (PD) is a recessive disorder of the connective tissue caused by mutations in the prolidase, a specific peptidase, cleaving the dipeptides with a C-terminal prolyl and hydroxyprolyl residue. PD is a complex syndrome characterized mainly by intractable skin
Arkadiusz Surazynski et al.
European journal of pharmacology, 649(1-3), 115-119 (2010-09-28)
Transforming growth factor beta 1 (TGF β1) is a protein that in most cells control proliferation and differentiation. One of the best characterized functions of TGF β1 is stimulation of collagen biosynthesis that may lead to tissue fibrosis. Several reports
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