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Merck

C4135

Sigma-Aldrich

氨基甲酰磷酸 二钠盐

≥80%

别名:

氨基甲酰磷酸二钠

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About This Item

线性分子式:
CH2NO5PNa2
CAS号:
分子量:
184.98
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

≥80%

形狀

powder

儲存溫度

−20°C

SMILES 字串

[Na].NC(=O)OP(O)(O)=O

InChI

1S/CH4NO5P.2Na/c2-1(3)7-8(4,5)6;;/h(H2,2,3)(H2,4,5,6);;/q;2*+1/p-2

InChI 密鑰

ZZRCKSSPGJOTEE-UHFFFAOYSA-L

一般說明

氨基甲酰磷酸二钠盐 (CPC) 能够活化羧酸并将其转化为相应的混合酸酐,是重要的有机合成试剂。在合成环肽和大环化合物时,它可活化羧酸并促进环化反应。

應用

  • Carbamoyl phosphate and its substitutes for the uracil synthesis in origins of life scenarios(氨基甲酰磷酸及其取代物在生命起源中用于尿嘧啶合成):该研究探索了在早期地球条件下,氨基甲酰磷酸二钠盐在尿嘧啶(RNA的基础成分)生物前合成中的作用(LMP Ter-Ovanessian et al., 2021)。
  • Building the uracil skeleton in primitive ponds at the origins of life: carbamoylation of aspartic acid(天冬氨酸氨基甲酰化,在生命起源的原始池塘中构建尿嘧啶骨架):进一步研究氨基甲酰磷酸在生物前合成中的重要性,在早期地球场景中,它可能与天冬氨酸作用形成尿嘧啶(LMP Ter-Ovanessian, JF Lambert, MC Maurel, 2022)。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Eduardo H Morales et al.
BMC microbiology, 12, 63-63 (2012-05-02)
Hydrogen peroxide (H2O2) and hypochlorous acid (HOCl) are reactive oxygen species that are part of the oxidative burst encountered by Salmonella enterica serovar Typhimurium (S. Typhimurium) upon internalization by phagocytic cells. In order to survive, bacteria must sense these signals
Dan M Park et al.
ACS synthetic biology, 8(4), 807-817 (2019-03-22)
The ability to detect uranium (U) through environmental monitoring is of critical importance for informing water resource protection and nonproliferation efforts. While technologies exist for environmental U detection, wide-area environmental monitoring, i.e. sampling coverage over large areas not known to
P Guerrero et al.
Microbiology (Reading, England), 159(Pt 10), 2049-2057 (2013-08-07)
In response to antibiotics, bacteria activate regulatory systems that control the expression of genes that participate in detoxifying these compounds, like multidrug efflux systems. We previously demonstrated that the BaeSR two-component system from Salmonella enterica serovar Typhimurium (S. Typhimurium) participates

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