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Merck

C3878

Sigma-Aldrich

绿原酸

≥95% (titration)

别名:

CGA, 1,4,5-三羟基环己烷甲酸3-(3,4-二羟基肉桂酸), 3-(3,4-二羟基肉桂酰)奎宁酸

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About This Item

经验公式(希尔记法):
C16H18O9
CAS号:
分子量:
354.31
EC號碼:
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

≥95% (titration)

形狀

powder

mp

210 °C (dec.) (lit.)

SMILES 字串

O[C@@H]1C[C@](O)(C[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@@H]1O)C(O)=O

InChI

1S/C16H18O9/c17-9-3-1-8(5-10(9)18)2-4-13(20)25-12-7-16(24,15(22)23)6-11(19)14(12)21/h1-5,11-12,14,17-19,21,24H,6-7H2,(H,22,23)/b4-2+/t11-,12-,14-,16+/m1/s1

InChI 密鑰

CWVRJTMFETXNAD-JUHZACGLSA-N

基因資訊

rat ... G6pc(25634)

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一般說明

绿原酸是一种生物活性多酚类化合物,主要存在在许多植物,比如咖啡中。它是一种有效的神经保护剂还具有抗病毒,抗真菌抗氧化和抗肿瘤特性。CGA同样也参与调解葡萄糖和脂代谢,提高胰岛素敏感度。
绿原酸是一种肉桂酸酯,在双金属纳米颗粒合成中用作还原剂和稳定剂。

應用

  • Antioxidant and Phenolic Profiles: A study detailed the antioxidant and phenolic profiles of Thai medicinal plants, including chlorogenic acid, to support functional food and pharmaceutical development, highlighting its potential applications in enhancing food functionality and health benefits (Wanyo et al., 2024).
  • Intravesical Therapy for Cystitis: Research demonstrated the use of chlorogenic acid in intravesical therapy to modify acute voiding behavior in mice with systemic lipopolysaccharide inflammation-induced cystitis, suggesting therapeutic potential in bladder disorders (Yeh et al., 2024).
  • Cardioprotection in Chemotherapy: A hydroethanolic extract containing chlorogenic acid was investigated for its role in mitigating doxorubicin-induced cardiotoxicity through mitochondrial protection mediated by AMPK-PGC-1α-SOD, underscoring its potential in protective strategies against chemotherapy-induced cardiac damage (Song et al., 2024).
  • Nutritional Delivery and Food Industry: A review discussed chlorogenic acid′s role in nutrition delivery and its implications in the food industry, proposing its use as nanoparticles for active food packaging application. (Hu et al., 2024).

注意

在乙醇中可生成浑浊溶液

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Chlorogenic acid and caffeic acid are absorbed in humans
Olthof MR
The Journal of Nutrition, 131(1), 66-71 (2001)
Shp2 regulates chlorogenic acid-induced proliferation and adipogenic differentiation of bone marrow-derived mesenchymal stem cells in adipogenesis
Zhou RP
Molecular Medicine Reports, 11(6), 4489-4495 (2015)
Alexandros Priftis et al.
Mechanisms of ageing and development, 172, 115-122 (2017-11-28)
Coffee and grape contain various bioactive compounds like polyphenols that may exert beneficial effects, especially antioxidant activity, on human health upon consumption. However, the molecular mechanisms through which these effects are achieved are not fully elucidated. Thus, in the present
Roles of chlorogenic acid on regulating glucose and lipids metabolism: a review
Meng S
Evidence-Based Complementary and Alternative Medicine : ECAM (2013)
Computational screen and experimental validation of anti-influenza effects of quercetin and chlorogenic acid from traditional Chinese medicine
Liu Z
Scientific Reports, 6, 19095-19095 (2016)

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