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Merck

C11804

Sigma-Aldrich

对磺酰胺苯甲酸

97%

别名:

4-磺酰氨基苯甲酸, 4-羧基苯磺酰胺

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About This Item

线性分子式:
HO2CC6H4SO2NH2
CAS号:
分子量:
201.20
Beilstein:
1875393
EC號碼:
MDL號碼:
分類程式碼代碼:
12352108
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

97%

形狀

powder

反應適用性

reagent type: cross-linking reagent

mp

285-295 °C (lit.)

官能基

carboxylic acid
sulfonamide

SMILES 字串

O=S(C(C=C1)=CC=C1C(O)=O)(N)=O

InChI

1S/C7H7NO4S/c8-13(11,12)6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)

InChI 密鑰

UCAGLBKTLXCODC-UHFFFAOYSA-N

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一般說明

对氨磺酰苯甲酸别名对羧基苯磺酰胺,是苯甲酸的磺酰胺衍生物。广泛用作有机合成的交联剂。

應用

对氨磺酰苯甲酸可用于合成对氨磺酰苯甲酰氯和异氰酸衍生物。也可用于醇的酯化反应。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Jean-Yves Winum et al.
Journal of medicinal chemistry, 48(6), 2121-2125 (2005-03-18)
Targeting proteins overexpressed in hypoxic tumors is as an important means of controlling cancer disease. One such protein is the carbonic anhydrase (CA) isoenzyme IX, which in some types of tumors is overexpressed 150-200-fold. We report here a series of
H C Palfrey et al.
The American journal of physiology, 246(3 Pt 1), C242-C246 (1984-03-01)
The secretory response of isolated perfused shark rectal gland was characterized with respect to its inhibition by a chemically related series of 5-sulfamoylbenzoic acid derivatives and certain phenoxyacetic acid derivatives. Maximal fluid and salt secretion was elicited with dibutyryl adenosine
Tiffani A Greene et al.
PloS one, 6(5), e20123-e20123 (2011-06-02)
Bitter taste stimuli are detected by a diverse family of G protein-coupled receptors (GPCRs) expressed in gustatory cells. Each bitter taste receptor (TAS2R) responds to an array of compounds, many of which are toxic and can be found in nature.
Daniel J Orton et al.
Analytical chemistry, 90(1), 737-744 (2017-11-22)
To better understand disease conditions and environmental perturbations, multiomic studies combining proteomic, lipidomic, and metabolomic analyses are vastly increasing in popularity. In a multiomic study, a single sample is typically extracted in multiple ways, and various analyses are performed using
Daniela Vullo et al.
Bioorganic & medicinal chemistry letters, 15(4), 963-969 (2005-02-03)
The inhibition of a newly cloned human carbonic anhydrase (CA, EC 4.2.1.1), isozyme XII (hCA XII), has been investigated with a series of sulfonamides, including some clinically used derivatives (acetazolamide, methazolamide, ethoxzolamide, dichlorophenamide, dorzolamide, brinzolamide, benzolamide, and sulpiride, or indisulam

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