934372

MC-Val-Cit-PAB-PNP

≥95%

• 别名: L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N⁵-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-
• 经验公式（希尔记法）: C₃₅H₄₃N₇O₁₁
• CAS号: 159857-81-5
• 分子量: 737.76
• Beilstein: 10322169
• MDL號碼: MFCD22200431
• 分類程式碼代碼: 12352200
• PubChem物質ID: 468592337
• NACRES: NA.22

属性

• 品質等級: 100
• 化驗: ≥95%
• 形狀: powder
• 儲存溫度: 2-8°C
• SMILES 字串: [N+](=O)([O-])c1ccc(cc1)OC(=O)OCc2ccc(cc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CCCCCN3C(=O)C=CC3=O)C(C)C)CCCNC(=O)N

说明

應用

This is a bifunctional cathepsin cleavable linker used in the construction of antibody drug conjugates (ADC).

特點和優勢

The maleimide functionality can be used for bioconjugation to thiols in monoclonal antibodies while the activated carbonate esters can be used for construction of carbamate linkages with amine containing payloads.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable