911690

C5 Lenalidomide

≥95%

• 别名: 3-(5-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione, E3 ligase ligand, Ligand for PROTAC^® research
• 经验公式（希尔记法）: C₁₃H₁₃N₃O₃
• CAS号: 191732-70-4
• 分子量: 259.26
• MDL號碼: MFCD31692701
• 分類程式碼代碼: 12352101
• NACRES: NA.22

属性

• ligand: C5 Lenalidomide
• 品質等級: 100
• 化驗: ≥95%
• 形狀: powder
• 反應適用性: reagent type: ligand
• 儲存溫度: 2-8°C
• SMILES 字串: NC1=CC=C2C(CN(C3CCC(NC3=O)=O)C2=O)=C1

说明

應用

C5 Lenalidomide is a derivative of the Cereblon (CRBN)-binding ligand lenalidomide, which possesses an amine at the C4 position. C5 Lenalidomide can be used to bind the CRBN E3 ubiquitin ligase in targeted protein degradation research or in the synthesis of protein degraders with a C5 exit vector. Learn more about proteolysis-targeting chimeras (PROTACs) and the building blocks to design them in our Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

其他說明

Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation

Portal: Building PROTAC^® Degraders for Targeted Protein Degradation

Amino-substituted thalidomide analogs: potent inhibitors of TNF-alpha production

Targeted Protein Degradation by Small Molecules

法律資訊

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

安全信息

• 象形圖: GHS08
• 訊號詞: Warning
• 危險聲明: H361d,H373
• 防範說明: P202 - P260 - P280 - P308 + P313 - P405 - P501
• 危險分類: Repr. 2 - STOT RE 2
• 標靶器官: Blood
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable