推荐产品
等級
technical
品質等級
化驗
≥80% (T)
形狀
solid
反應適用性
reagent type: cross-linking reagent
儲存溫度
−20°C
SMILES 字串
CC(C)(C)OC(=O)CCOCCOCCOCCN
InChI
1S/C13H27NO5/c1-13(2,3)19-12(15)4-6-16-8-10-18-11-9-17-7-5-14/h4-11,14H2,1-3H3
InChI 密鑰
CWFSAZJIJBTKRC-UHFFFAOYSA-N
應用
tert-Butyl 12-amino-4,7,10-trioxadodecanoate is generally used as a spacer or linker in bioconjugate chemistry. Some of its applications are:
- Synthesis of the tetanus-toxin conjugate of MUC1 glycopeptide antigen, as a potential antitumor vaccine.
- Synthesis of self-assembled monolayer-based surface-enhanced raman scattering (SERS) labels for immuno-SERS microscopy.
- Synthesis of polycationic adamantane-based dendrons for cell imaging.
- Synthesis of phthalocyanine (Pc)-peptide conjugates as potential fluorescence imaging agents for cancers overexpressing epidermal growth factor receptors (EGFR).
其他說明
合成组合化学所用间隔臂的中间体
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
337.5 °F
閃點(°C)
169.7 °C
個人防護裝備
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
其他客户在看
Towards the Development of Antitumor Vaccines: A Synthetic Conjugate of a Tumor?Associated MUC1 Glycopeptide Antigen and a Tetanus Toxin Epitope.
Angewandte Chemie (International Edition in English), 40(2), 366-369 (2001)
Phthalocyanine?peptide conjugates for epidermal growth factor receptor targeting.
Journal of Medicinal Chemistry, 55(8), 3725-3738 (2012)
Water soluble SERS labels comprising a SAM with dual spacers for controlled bioconjugation.
Physical Chemistry Chemical Physics, 11(34), 7499-7504 (2009)
Polycationic adamantane-based dendrons of different generations display high cellular uptake without triggering cytotoxicity.
Journal of the American Chemical Society, 136(2), 810-819 (2014)
Angewandte Chemie (International Edition in English), 113, 379-379 (2001)
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