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705993

Sigma-Aldrich

3-表-25-羟基维生素 D3

98% (CP)

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About This Item

经验公式（希尔记法）:
C27H44O2
CAS号:
73809-05-9
分子量:
400.64
MDL號碼:
MFCD11656130
分類程式碼代碼:
12352205
PubChem物質ID:
329762603
NACRES:
NA.24

化驗

98% (CP)

形狀

powder

技術

mass spectrometry (MS): suitable

顏色

white to off-white

質量偏移

M+3

儲存溫度

−20°C

SMILES 字串

C[C@@]12[C@](CC[C@]2([H])[C@@H](CCCC(C)(O)C)C)([H])/C(CCC1)=C/C=C3C[C@H](O)CCC/3=C

InChI

1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23-,24-,25+,27-/m1/s1

InChI 密鑰

JWUBBDSIWDLEOM-UEGFJKGBSA-N

相关类别

應用

3-表-25-羟基维生D3又称为3-epi-25(OH)D3。它是维生素D3在肝脏中形成的代谢物。3-epi-25(OH)D3可作为生物标记物测定维生素D的体内状态。还可作为分析标准品，测定人血清中的3-epi-25(OH)D3分子浓度。

包裝

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相關產品

产品编号
说明
价格

象形圖

Skull and crossbonesHealth hazard
GHS06,GHS08

訊號詞

Danger

危險分類

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

从最新的版本中选择一种：

分析证书(COA)

Lot/Batch Number
MBBD2162
MBBC6999
MBBC5952
MBBC2745
MBBB9224V

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Qi Wang et al.
The Journal of steroid biochemistry and molecular biology, 135, 43-50 (2013-01-22)
Vitamin D has been known to be closely associated with diabetes and periodontitis while the underlying mechanism has yet to be clarified. The present study aimed to discover the effect of 25-hydroxyvitamin D3 (25-OHD3) on glycemic control and periodontal health
Violetta Csakvary et al.
Bone, 54(1), 106-112 (2013-02-07)
The conditions that define bone development in prepuberty profoundly influence bone health later in life. We aimed to reveal important determinants of bone mass in Tanner stage I. We studied 84 healthy children (43 girls and 41 boys) aged 7
Andrzej Slominski et al.
The Journal of clinical endocrinology and metabolism, 98(2), E298-E303 (2013-01-09)
There is no effective treatment for systemic sclerosis and related fibrosing diseases. Recently the action of CYP11A1 on vitamin D(3) was shown to produce biologically active 20S-hydroxyvitamin D [20(OH)D(3)] and 20,23(OH)(2)D(3), 20,22(OH)(2)D(3), and 17,20,23(OH)(3)D(3). Because 20(OH)D(3) is noncalcemic (nontoxic) in
Hataikarn Nimitphong et al.
PloS one, 7(12), e52171-e52171 (2012-12-29)
1,25(OH)(2)D(3) inhibits adipogenesis in mouse 3T3-L1 adipocytes, but little is known about its effects or local metabolism in human adipose tissue. We showed that vitamin D receptor (VDR) and 1α-hydroxylase (CYP27B1), the enzyme that activates 25(OH)D(3) to 1,25(OH)(2)D(3), were expressed
Vitamin D assays and the definition of hypovitaminosis D: results from the First International Conference on Controversies in Vitamin D
Sempos CT, et al.
British Journal of Clinical Pharmacology, 84(10), 2194-2207 (2018)
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Novel sample prep technique coupled with the unique selectivity of the Ascentis Express F5 column enables a fast and simplified bioanalytical method for associated vitamin D metabolites.

Method Optimization for LC-MS Analysis of Vitamin D Metabolite Critical Pairs in Serum

Novel sample prep technique coupled with the unique selectivity of the Ascentis Express F5 column enables a fast and simplified bioanalytical method for associated vitamin D metabolites.

Method Optimization for LC-MS Analysis of Vitamin D Metabolite Critical Pairs in Serum

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Improvement in LC/MS Analysis of Vitamin D Metabolites in Serum by Leveraging Column Selectivity and Effective Sample Prep

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