677191

(R)-(+)-α,α-二苯基-2-吡咯烷甲醇三甲基硅基醚

96%

• 别名: (2R)-2-[二苯基[(三甲基硅基)氧基]甲基]吡咯烷, (R)-α,α-二苯基脯氨醇三甲基硅基醚, (R)-2-[Diphenyl(trimethylsilanyloxy)methyl]pyrrolidine
• 经验公式（希尔记法）: C₂₀H₂₇NOSi
• CAS号: 943757-71-9
• 分子量: 325.52
• MDL號碼: MFCD09265100
• 分類程式碼代碼: 12352005
• PubChem物質ID: 24885355
• NACRES: NA.22

属性

• 化驗: 96%
• 形狀: solid
• 光學活性: [α]22/D +52±5°, c = 1 in chloroform
• 折射率: n20/D 1.5509
• 密度: 1.0459 g/mL at 25 °C
• 官能基: phenyl
• 儲存溫度: 2-8°C
• SMILES 字串: C[Si](C)(C)OC([C@H]1CCCN1)(c2ccccc2)c3ccccc3
• InChI: 1S/C20H27NOSi/c1-23(2,3)22-20(19-15-10-16-21-19,17-11-6-4-7-12-17)18-13-8-5-9-14-18/h4-9,11-14,19,21H,10,15-16H2,1-3H3/t19-/m1/s1
• InChI 密鑰: RSUHWMSTWSSNOW-LJQANCHMSA-N

说明

一般說明

(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether is a diarylprolinol silyl ether organocatalyst.

應用

(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether can be used as a catalyst to synthesize:

• Glycofused tricyclic derivatives, which are used in the development of amyloid β-peptide diagnostic tools.
• Cyclohexene carbaldehyde derivatives by reacting benzoylnitromethane with aliphatic enals.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves