536822

PAMAM-OH 树枝状聚合物，第6代 溶液

5 wt. % in methanol

• 线性分子式: [NH₂(CH₂)₂NH₂]:(G=6);dendri PAMAM(NHCH₂CH₂OH)₂₅₆
• 分子量: 58298.21
• MDL號碼: MFCD00197936
• 分類程式碼代碼: 12162002
• NACRES: NA.25

属性

• 描述: amidoethanol surface groups
• 品質等級: 100
• 形狀: liquid
• 分子量: generation 6
• 特點: core type ethylenediamine core (2-carbon core)
• 濃度: 5 wt. % in methanol
• 號表面基團: 256
• 折射率: n20/D 1.336
• 密度: 0.807 g/mL at 25 °C
• 儲存溫度: 2-8°C

说明

一般說明

PAMAM-OH (poly(amidoamine) dendrimers are highly branched core-shell nanostructures with surface hydroxyl groups. The presence of hydroxyl groups on the surface of the PAMAM-OH dendrimer molecule leads to stronger interaction with the components of the cell membrane via the formation of hydrogen bonds. This type of interaction can modify the properties and function of cell membranes. PAMAM-OH dendrimers also have an advantage over PAMAM dendrimers in terms of cytotoxicity and aggregation problems because of the absence of amine functionality.

應用

PAMAM-OH dendrimer can be used to formulate poorly water-soluble drugs to increase water solubility, and therefore enhance the bioavailability of these drugs. It can also be applied to catalysts and organic molecules, where dendrimers function as solubility enhancers and modifiers.

外觀

含有 256 个表面羟基。

法律資訊

Dendritech®, Inc. 制造
使用及制造受 Dow Chemical Company 拥有的专利所保护。

Dendritech is a registered trademark of Dendritech, Inc.

安全信息

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H225,H301 + H311 + H331,H370
• 防範說明: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 標靶器官: Eyes
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: 51.8 °F - closed cup
• 閃點（°C）: 11 °C - closed cup