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Sigma-Aldrich

Fmoc-L-天冬氨酸4-叔丁酯

≥98.0% (HPLC), for peptide synthesis

别名:

Fmoc-L-天冬氨酸 4-叔丁酯

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About This Item

经验公式（希尔记法）:
C23H25NO6
CAS号:
71989-14-5
分子量:
411.45
Beilstein:
3635671
EC號碼:
276-251-7
MDL號碼:
MFCD00037131
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
57651040
NACRES:
NA.26

product name

Fmoc-L-天冬氨酸4-叔丁酯, ≥98.0% (HPLC)

化驗

≥98.0% (HPLC)

形狀

powder

光學活性

[α]20/D −24±2°, c = 1% in DMF

反應適用性

reaction type: Fmoc solid-phase peptide synthesis

mp

148-150 °C (dec.)

應用

peptide synthesis

官能基

Fmoc

儲存溫度

2-8°C

SMILES 字串

CC(C)(C)OC(=O)C[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

InChI

1S/C23H25NO6/c1-23(2,3)30-20(25)12-19(21(26)27)24-22(28)29-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,26,27)/t19-/m0/s1

InChI 密鑰

FODJWPHPWBKDON-IBGZPJMESA-N

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相关类别

一般說明

Fmoc-Asp(OtBu)-OH又称为Fmoc-L-天冬氨酸4-叔丁酯，在固相多肽合成中用作Fmoc-氨基酸类保护基团。

應用

Fmoc-Asp(OtBu)-OH可用于在Fmoc肽固相合成中防止天冬氨酰亚胺副产物的形成。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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Fengyang Xu et al.
ACS applied materials & interfaces, 8(44), 29906-29914 (2016-10-21)
In this work, we reported the generation of a novel supramolecular hydrogelator from a peptide derivative which consisted of a structural motif (e.g., Fc-FF) for supramolecular self-assembly and a functional moiety (e.g., RGD) for integrin binding. Following self-assembly in water
Jisi Zhao et al.
Molecules (Basel, Switzerland), 24(4) (2019-03-03)
Photodynamic therapy (PDT) is an established therapeutic modality for the management of cancers. Conjugation with tumor-specific small molecule ligands (e.g., short peptides or peptidomimetics) could increase the tumor targeting of PDT agents, which is very important for improving the outcome
R Ashton Lavoie et al.
International journal of molecular sciences, 20(7) (2019-04-11)
The growing integration of quality-by-design (QbD) concepts in biomanufacturing calls for a detailed and quantitative knowledge of the profile of impurities and their impact on the product safety and efficacy. Particularly valuable is the determination of the residual level of
R Ashton Lavoie et al.
Biotechnology and bioengineering, 117(2), 438-452 (2019-10-28)
The clearance of host cell proteins (HCPs) is of crucial importance in biomanufacturing, given their diversity in composition, structure, abundance, and occasional structural homology with the product. The current approach to HCP clearance in the manufacturing of monoclonal antibodies (mAbs)
Stefan Eissler et al.
Journal of peptide science : an official publication of the European Peptide Society, 23(10), 757-762 (2017-06-22)
In solid-phase peptide synthesis, the nominal batch size is calculated using the starting resin substitution and the mass of the starting resin. The starting resin substitution constitutes the basis for the calculation of a whole set of important process parameters
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