推荐产品
化驗
95%
光學活性
[α]22/D −44°, c = 1 in chloroform
mp
74-76 °C (lit.)
SMILES 字串
CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2
InChI
1S/C10H18N2O2/c1-10(2,3)14-9(13)12-6-7-4-8(12)5-11-7/h7-8,11H,4-6H2,1-3H3/t7-,8-/m0/s1
InChI 密鑰
UXAWXZDXVOYLII-YUMQZZPRSA-N
應用
(1S,4S)-(-)-2-Boc-2,5-diazabicyclo[2.2.1]heptane may be used in the preparation of 2-boc-5-(4-nitrophenyl)-2,5-diaza-bicyclo[2.2.1]heptane by reacting with p-nitrobenzene.
It may also be used to develop:
It may also be used to develop:
- indazolylpyrazolo[1,5-a]pyrimidine analogs based B-Raf inhibitors
- CCR2 antagonists
- α4β2 nicotinic acetylcholine receptor (nAChR) partial agonists
- azabicyclic sulfonamide based 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
4-(Phenylaminomethylene) isoquinoline-1, 3 (2H,4H)-diones as potent and selective inhibitors of the cyclin-dependent kinase 4 (CDK4).
Journal of Medicinal Chemistry, 51(12), 3507-3525 (2008)
Design and synthesis of novel CCR2 antagonists: Investigation of non-aryl/heteroaryl binding motifs.
Bioorganic & Medicinal Chemistry Letters, 21(6), 1827-1831 (2011)
Synthesis and biological evaluation of novel hybrids of highly potent and selective a4?2-Nicotinic acetylcholine receptor (nAChR) partial agonists.
European Journal of Medicinal Chemistry, 124, 689-697 (2016)
Indazolylpyrazolopyrimidine as highly potent B-Raf inhibitors with in vivo activity.
Journal of Medicinal Chemistry, 53(21), 7874-7878 (2010)
Azabicyclic sulfonamides as potent 11?-HSD1 inhibitors.
Bioorganic & Medicinal Chemistry Letters, 20(5), 1551-1554 (2010)
实验方案
GC Analysis of Grob Test Mix on SLB®-IL76i
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