推荐产品
化驗
98%
mp
79-82 °C (lit.)
SMILES 字串
CC1=Nc2ccccc2C(=O)O1
InChI
1S/C9H7NO2/c1-6-10-8-5-3-2-4-7(8)9(11)12-6/h2-5H,1H3
InChI 密鑰
WMQSKECCMQRJRX-UHFFFAOYSA-N
訊號詞
Warning
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
B Siedle et al.
Bioorganic & medicinal chemistry, 10(9), 2855-2861 (2002-07-12)
Human neutrophil elastase (HNE) is a serine protease that has been implicated in the abnormal turnover of connective tissue proteins and has been described as an important pathogenic factor in several inflammatory diseases such as rheumatoid arthritis or cystic fibrosis.
Reactivity of 4H-3,1-benzoxazin-4-ones towards nitrogen and carbon nucleophilic reagents: applications to the synthesis of new heterocycles.
Madkour HMF.
ARKIVOC (Gainesville, FL, United States), 1, 36-54 (2004)
A Simple Synthesis of 2-Substituted-4 H-3, 1-benzoxazin-4-ones by Palladium-Catalyzed Cyclocarbonylation of o-Iodoanilines with Acid Chlorides.
Chitchamai L and Alper H.
Organic Letters, 1(10), 1619-1622 (1999)
L Hedstrom et al.
Biochemistry, 23(8), 1753-1759 (1984-04-10)
The benzoxazinones 2-ethoxy-4H-3,1- benzoxazin -4-one (1a) and 2-(trifluoromethyl)-4H-3,1- benzoxazin -4-one (1d) inactivate chymotrypsin. The inactivation is stoichiometric and proceeds with rate constants of 7 X 10(5) M-1 min-1 and greater than 4 X 10(6) M-1 min-1, respectively. The inactivated enzyme
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