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Merck

391913

Sigma-Aldrich

(R)-(+)-6-羟基-2,5,7,8-四甲基色满-2-羧酸

98%

别名:

(2R)-3,4-二氢-6-羟基-2,5,7,8-四甲基-2H-1-苯并吡喃-2-甲酸, (R)-Trolox

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About This Item

经验公式(希尔记法):
C14H18O4
CAS号:
分子量:
250.29
MDL號碼:
分類程式碼代碼:
12352005
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

98%

形狀

solid

光學活性

[α]27/D +65°, c = 1.2 in ethanol

mp

162 °C (dec.) (lit.)

官能基

carboxylic acid

SMILES 字串

Cc1c(C)c2O[C@](C)(CCc2c(C)c1O)C(O)=O

InChI

1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)/t14-/m1/s1

InChI 密鑰

GLEVLJDDWXEYCO-CQSZACIVSA-N

一般說明

( R )-(+)-6-羟基-2,5,7,8-四甲基色-2-羧酸,为维生素 E 类似物,是一种蘑菇酪氨酸酶抑制剂。

應用

当设计基于γ-氨基丁酸(GABA)的抗应激剂时。(R) - (+) - 6-羟基-2,5,7,8-四甲基色满-2-羧酸可用于结合抗氧化性能。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Yu L.
Journal of Agricultural and Food Chemistry, 51(8), 2344-2347 (2003)
Novel compounds designed as antistress agents.
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Journal of Medicinal Chemistry, 52(22), 7315-7318 (2009)
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Acta poloniae pharmaceutica, 74(2), 670-678 (2018-04-07)
Polyphenol rich extracts obtained from cistus herb (Cistus incanus L.) and pomegranate peels (Punica granatunm L.) added at high concentrations (25-100 pg/mL) to V79 (Chinese hamster lung fibroblast) cell cultures, markedly increased intracellular level of ROS (reactive oxygen species). Also
Helena Moreira et al.
Acta poloniae pharmaceutica, 74(2), 688-698 (2018-04-07)
Polyphenol rich extracts obtained from cistus herb (Cistus incanus L.) and pomegranate peel (Punica granatum L.) exhibited significant antioxidant activity in V79 cell culture (Chinese hamster lung fibroblasts) -cistus extract reduced intracellular content of reactive oxygen species (ROS) by 30-40%

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