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Merck

383384

Sigma-Aldrich

5′-氯-2′-羟基苯乙酮

99%

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About This Item

线性分子式:
ClC6H3(OH)COCH3
CAS号:
分子量:
170.59
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

99%

形狀

solid

bp

126-128 °C/28 mmHg (lit.)

mp

54-56 °C (lit.)

官能基

chloro
ketone

SMILES 字串

CC(=O)c1cc(Cl)ccc1O

InChI

1S/C8H7ClO2/c1-5(10)7-4-6(9)2-3-8(7)11/h2-4,11H,1H3

InChI 密鑰

XTGCUDZCCIRWHL-UHFFFAOYSA-N

一般說明

5′-Chloro-2′-hydroxyacetophenone (5-chloro-2- hydroxyacetophenone) on condensation with salicylhydrazide yields Schiff base, which is reported to form copper(II) complexes. Dipole moment of 5-chloro-2- hydroxyacetophenone has been evaluated in benzene solution.

應用

5′-Chloro-2′-hydroxyacetophenone (5-chloro-2- hydroxyacetophenone) may be used in the synthesis of:
  • 6-chloro-2-methyl-4H-chrome-4-one
  • 1-(2-hydroxyphenyl)-5-phenyl-2,4-pentadien-1-ones
  • 1-(2-hydroxyphenyl)-5-phenyl-2,4-pentadien-1-ones
  • 2-styrenyl allyl ether

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Synthesis and characterization of copper (II) complexes with a tridentate schiff base ligand derived from 5-chloro-2-hydroxyacetophenone and salicylhydrazide. X-ray structure of copper (II)(5-chloro-2-hydroxyacetophenone-salicylhydrazide) dimethylformamide.
Dance JM, et al.
Inorgorganica Chimica Acta, 162(2), 239-244 (1989)
Studies on the Intramolecular Hydrogen Bond in Conjugated Systems by the Measurements of Dipole Moments. II. Salicylaldehyde and o-Hydroxyacetophenone
Eda B and Ito K.
Bulletin of the Chemical Society of Japan, 30(2), 164-167 (1957)
A Highly Efficient and Practical Synthesis of Chromene Derivatives Using Ring-Closing Olefin Metathesis.
Sukbok Chang et al.
The Journal of organic chemistry, 63(3), 864-866 (2001-10-24)
T Keim et al.
Journal of industrial microbiology & biotechnology, 23(4-5), 359-363 (2001-06-26)
Due to their physicochemical and toxicological properties, polychlorinated dibenzofurans are regarded as a class of compounds providing reason for serious environmental concern. While the nonhalogenated basic structure dibenzofuran is effectively mineralized by appropriate bacterial strains, its polychlorinated derivatives are not.
Nicoletta Desideri et al.
Antiviral chemistry & chemotherapy, 14(4), 195-203 (2003-10-30)
Recently, we identified 2-styrylchromones as a new class of antirhinovirus flavonoids with moderate activity against both rhinovirus groups A and B. In order to improve the antiviral effect of the first series of tested 2-styrylchromones, a hydroxy or methoxy group

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