298891

(4R,5S)-(+)-4-甲基-5-苯基-2-噁唑啉酮

99%

• 别名: (4R,5S)-4-甲基-5-苯基-2-噁唑啉酮
• 经验公式（希尔记法）: C₁₀H₁₁NO₂
• CAS号: 77943-39-6
• 分子量: 177.20
• Beilstein: 1211705
• MDL號碼: MFCD00010845
• 分類程式碼代碼: 12352005
• PubChem物質ID: 24858003
• NACRES: NA.22

属性

• 化驗: 99%
• 形狀: solid
• 光學活性: [α]18/D +168°, c = 2 in chloroform
• 光學純度: ee: 98% (GLC)
• mp: 121-123 °C (lit.)
• SMILES 字串: C[C@H]1NC(=O)O[C@H]1c2ccccc2
• InChI: 1S/C10H11NO2/c1-7-9(13-10(12)11-7)8-5-3-2-4-6-8/h2-7,9H,1H3,(H,11,12)/t7-,9-/m1/s1
• InChI 密鑰: PPIBJOQGAJBQDF-VXNVDRBHSA-N

说明

應用

Evan′s chiral auxiliary (4R,5S)-(+)-4-Methyl-5-phenyl-2-oxazolidinone reacts with carboxylic acids to produce corresponding acyl derivatives in the presence of a diisopropylcarbodiimide reagent. It can also employed in the preparation of N-sulfinyloxazolidinone reagent (chiral sulfinyl transfer reagent), which reacts with nucleophiles such as Grignard reagents, enolates, and metalated amides to produce the chiral sulfoxides, sulfinate esters, and sulfonamides.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)