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15404

Sigma-Aldrich

N-Boc-1,4-丁二胺

≥97.0% (GC/NT)

别名:

N-(4-氨丁基)氨基甲酸叔丁酯, N-Boc-1,4-二氨基丁烷

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About This Item

线性分子式:
(CH3)3COCONH(CH2)4NH2
CAS号:
68076-36-8
分子量:
188.27
Beilstein:
1937878
MDL號碼:
MFCD00210019
分類程式碼代碼:
12352116
PubChem物質ID:
57647412
NACRES:
NA.22

品質等級

100

化驗

≥97.0% (GC/NT)

反應適用性

reagent type: cross-linking reagent

折射率

n20/D 1.460

密度

0.984 g/mL at 20 °C (lit.)

官能基

Boc
amine

SMILES 字串

NCCCCNC(OC(C)(C)C)=O

InChI

1S/C9H20N2O2/c1-9(2,3)13-8(12)11-7-5-4-6-10/h4-7,10H2,1-3H3,(H,11,12)

InChI 密鑰

ZFQWJXFJJZUVPI-UHFFFAOYSA-N

相关类别

應用

  • 羧基-硅烷涂覆氧化铁纳米颗粒：详述采用N-Boc-1,4-丁二胺修饰氧化铁纳米颗粒用于成像和药物递送(D Stanicki, S Boutry, S Laurent, et al., 2014)。访问文章。

其他說明

药理活性化合物的制备。亚精胺类似物的制备。C4-间隔基的引入。

象形圖

Corrosion
GHS05

訊號詞

Danger

危險聲明

H314

危險分類

Skin Corr. 1B

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類（WGK）

WGK 3

閃點（°F）

228.2 °F - closed cup

閃點（°C）

109.0 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

从最新的版本中选择一种：

分析证书(COA)

Lot/Batch Number
1142779V
1142779
015906/2
062192/1
015906/1

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N-Boc-4,7,10-三氧杂-1,13-十三烷二胺 ≥95.0% (NT)

Sigma-Aldrich

93113

N-Boc-4,7,10-三氧杂-1,13-十三烷二胺

Y Shai et al.
Biochemistry, 28(11), 4801-4806 (1989-05-30)
In the present study we synthesize 18F-labeled insulin of high specific radioactivity. A new prosthetic group methodology, in which [18F]fluoride displaces a bromide group of 4-(bromomethyl)-benzoylamine intermediates, was used. The 4-(fluoromethyl)benzoyl product was chemically stable. 18F-Labeled insulin retains the essential
L I Kruse et al.
Journal of medicinal chemistry, 32(2), 409-417 (1989-02-01)
In an attempt to identify a soluble oncodazole analogue that could be easily formulated, a series of substituted oncodazoles was synthesized and evaluated for tubulin binding affinity, in vitro cytotoxicity against cultured mouse B-16 cells, and ability to prolong lifespan
Hongyan Guo et al.
Journal of medicinal chemistry, 45(10), 2056-2063 (2002-05-03)
Several iron chelators containing alpha,beta-unsaturated hydroxamic acid motifs appended to a citric acid platform were synthesized. Mycobacterium paratuberculosis was then challenged to grow in the presence of a panel of siderophores (mycobactin J, deferrioxamine B, acinetoferrin, and nannochelin A) and
M. McWatt, G.J. Boons et al.
European Journal of Organic Chemistry, 2535-2535 (2001)
H.H. Wassermann et al
Tetrahedron, 58, 7177-7177 (2002)
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MRT - Mono-Boc-Protection of Diamines

Mono-Boc-protected diamines are versatile building blocks for chemical synthesis. Their production is a lot more challenging than the simple reaction scheme might imply, because the Boc-anhydride reagent cannot differentiate between the two identical amino moieties in the substrate.

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