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Merck

CACNA1E

calcium channel, voltage-dependent, R type, alpha 1E subunit

别名:
BII, CACH6, CACNL1A6, Cav2.3
物种:
UniProtKB ID:
基因ID:
  • Human(777) Summary: Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
  • Mouse(12290) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • Rat(54234) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • Zebrafish(567702) voltage-dependent R-type calcium channel subunit alpha-1E
  • cow(353113) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • domestic cat(101093985) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • dog(490305) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • chicken(424412) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • naked mole-rat(101701145) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • domestic guinea pig(100716749) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • sheep(101102503) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • Domestic Rabbit(100009403) calcium channel, voltage-dependent, R type, alpha 1E subunit

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Small Molecule - Allosteric Modulator

货号
说明
物种
加巴喷丁, United States Pharmacopeia (USP) Reference Standard,
物种
human
加巴喷丁标准液 CRM 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
加巴喷丁, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
普瑞巴林, European Pharmacopoeia (EP) Reference Standard,
物种
human
加巴喷丁标准液 CRM 溶液, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-CACNA1S antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-CACNA1S antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Monoclonal Anti-Dihydropyridine Receptor (α1 Subunit) antibody produced in mouse, clone 1A, buffered aqueous solution,
物种反应性
guinea pig, human, mouse, rabbit, rat
应用
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Blocker

货号
说明
物种
苯磺酸氨氯地平, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
维拉帕米 盐酸盐, United States Pharmacopeia (USP) Reference Standard,
物种
human
苯磺酸氨氯地平, ≥98% (HPLC),
物种
human
苯磺酸氨氯地平(钙拮抗药), United States Pharmacopeia (USP) Reference Standard,
物种
human
尼卡地平 盐酸盐, powder, ≥98%,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Cacna1e,
物种
mouse
MISSION® esiRNA, targeting human CACNA1E,
物种
human
MISSION® esiRNA, targeting human CACNA1S,
物种
human
MISSION® esiRNA, targeting mouse Cacna1s,
物种
mouse