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1356632

USP

Ketoprofen

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

2-(3-Benzoylphenyl)propionic acid

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About This Item

Formule empirique (notation de Hill):
C16H14O3
Numéro CAS:
22071-15-4
Poids moléculaire :
254.28
Numéro MDL:
MFCD00055790
Code UNSPSC :
41116107
ID de substance PubChem :
329750217
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

ketoprofen

Fabricant/nom de marque

USP

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

CC(C(O)=O)c1cccc(c1)C(=O)c2ccccc2

InChI

1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)

Clé InChI

DKYWVDODHFEZIM-UHFFFAOYSA-N

Informations sur le gène

human ... PTGS1(5742) , PTGS2(5743)

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Catégories apparentées

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ketoprofen USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Ketoprofen Capsules
  • Ketoprofen Extended-Release Capsules

Actions biochimiques/physiologiques

Composé anti-inflammatoire non stéroïdien spécifique de la COX-1.

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

K2000000

Ketoprofen, European Pharmacopoeia (EP) Reference Standard

K2000010

Ketoprofen impurity A, European Pharmacopoeia (EP) Reference Standard

K2000015

Ketoprofen impurity C, European Pharmacopoeia (EP) Reference Standard

1356643

Ketoprofen Related Compound A, United States Pharmacopeia (USP) Reference Standard

1356563

Ketoprofen Related Compound D hydrochloride, United States Pharmacopeia (USP) Reference Standard

1356552

Ketoprofen Related Compound C, United States Pharmacopeia (USP) Reference Standard

BP668

Ketoprofen, British Pharmacopoeia (BP) Reference Standard

BP667

Ketoprofen ethyl ester, British Pharmacopoeia (BP) Reference Standard

PHR2877

Ketoprofen Related Compound F, pharmaceutical secondary standard, certified reference material

PHR2955

Ketoprofen Related Compound D, pharmaceutical secondary standard, certified reference material

PHR3018

Ketoprofen Related Compound C, pharmaceutical secondary standard, certified reference material

Pictogrammes

Skull and crossbonesEnvironment
GHS06,GHS09

Mention d'avertissement

Danger

Mentions de danger

H301,H315,H319,H400

Classification des risques

Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Ketoprofen Related Compound D hydrochloride

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K2000015

Ketoprofen impurity C

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1179118

Dexketoprofen tromethamine

H Bagheri et al.
Drug safety, 22(5), 339-349 (2000-06-01)
The topical use of nonsteroidal anti-inflammatory drugs (NSAIDs), widely used for moderate acute and chronic painful conditions, is one of several strategies used to improve the tolerability profile of NSAIDs, particularly with regard to gastric and renal adverse effects. However
M Sugiura et al.
Contact dermatitis, 43(1), 16-19 (2000-07-21)
We report 4 cases of photocontact dermatitis due to ketoprofen, a non-steroidal anti-inflammatory drug derived from propionic acid. We carried out a skin biopsy to examine the amount of ketoprofen in the eruptive skin. We investigated the cross-reactions between tiaprofenic
Igor E Shohin et al.
Journal of pharmaceutical sciences, 101(10), 3593-3603 (2012-07-13)
Literature and experimental data relevant to the decision to allow a waiver of in vivo bioequivalence (BE) testing for the approval of immediate-release (IR) solid oral dosage forms containing ketoprofen are reviewed. Ketoprofen's solubility and permeability, its therapeutic use and
G Serrano et al.
Journal of the American Academy of Dermatology, 27(2 Pt 1), 204-208 (1992-08-01)
Photosensitivity reactions to fibric acid derivatives are not well understood and have been rarely reported. The aim of this study was to describe two cases of photosensitivity, one induced by fenofibrate and one by bezafibrate; to study the in vivo
Akihiko Ouchi et al.
Chirality, 14(1), 1-11 (2001-12-19)
The reactivity of organic molecules can be modified upon complexation with proteins: these changes can be different and more significant when the substrate is in an electronically excited state. Here we review UV, CD, and fluorescence spectroscopy studies on the
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