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MAK109

Sigma-Aldrich

LPL Activity Assay Kit

Supplied by Roar Biomedical, Inc.

Synonyme(s) :

Lipoprotein lipase activity assay kit

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About This Item

Code UNSPSC :
12161503
Nomenclature NACRES :
NA.84

Utilisation

sufficient for 100 fluorometric tests

Application(s)

pharmaceutical

Méthode de détection

fluorometric

Maladie(s) pertinente(s)

gastrointestinal diseases; cardiovascular diseases

Température de stockage

2-8°C

Informations sur le gène

human ... LPL(4023)

Description générale

Lipoprotein lipase (LPL) hydrolyzes triglycerides associated with VLDL.

Application

LPL Activity Assay Kit may be used for detection of LPL activity in plasma samples of patients with hypertriglyceridemia.

Adéquation

Suitable for the measurement of lipoprotein lipase activity in a variety of tissue samples

Principe

The LPL Activity Assay Kit includes a non-fluorescent substrate emulsion that becomes intensely fluorescent upon interaction with LPL and pre-hydrolyzed substrate for use as a standard to convert the fluorescence intensity reading to moles of reactant formed (λEx=370 nm/λEm=450 nm). The assay is not specific for LPL and will also detect hepatic lipase activity.

Remarque sur l'analyse

Learn more about Roar Assay Kits for Studies in Lipoprotein Metabolism.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Code de la classe de stockage

10 - Combustible liquids

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Ismayil Tasdelen et al.
PloS one, 8(5), e64284-e64284 (2013-05-23)
The transcription factor PPARγ is the key regulator of adipocyte differentiation, function and maintenance, and the cellular target of the insulin-sensitizing thiazolidinediones. Identification and functional characterization of genes regulated by PPARγ will therefore lead to a better understanding of adipocyte
Chaofeng Yang et al.
Nutrition & metabolism, 9(1), 94-94 (2012-10-31)
Endocrine FGF19 and FGF21 exert their effects on metabolic homeostasis through fibroblast growth factor receptor (FGFR) and co-factor betaKlotho (KLB). Ileal FGF19 regulates bile acid metabolism through specifically FGFR4-KLB in hepatocytes where FGFR1 is not significant. Both FGF19 and FGF21
Compound but non-linked heterozygous p. W14X and p. L279 V LPL gene mutations in a Chinese patient with long-term severe hypertriglyceridemia and recurrent acute pancreatitis.
Li X, et al.
Lipids in Health and Disease, 17(1), 144-144 (2018)
Evemie Dubé et al.
Biology of reproduction, 88(1), 16-16 (2012-12-12)
Gestational diabetes mellitus (GDM) is a common complication of pregnancy that is characterized by glucose intolerance, leads to dyslipidemia, and is aggravated by obesity. Cholesterol is taken up by the placenta as part of lipoproteins through the scavenger receptor class
Cedric H L Shackleton
Lipids, 47(1), 1-12 (2011-08-30)
In 1937 Butler and Marrian found large amounts of the steroid pregnanetriol in urine from a patient with the adrenogenital syndrome, a virilizing condition known to be caused by compromised adrenal secretion even in this pre-cortisol era. This introduced the
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Protocoles

LPL Activity Assay Protocol

Lipoprotein lipase (LPL) hydrolyzes triglycerides associated with VLDL.

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