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Key Documents

E3625

Sigma-Aldrich

16-Epiestriol

≥93% (HPLC)

Synonyme(s) :

1,3,5(10)-Estratriene-3,16β,17β-triol, 16β-Hydroxy-17β-estradiol, 3,16β,17β-Trihydroxy-1,3,5(10)-estratriene

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About This Item

Formule empirique (notation de Hill):
C18H24O3
Numéro CAS:
Poids moléculaire :
288.38
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352202
ID de substance PubChem :
Nomenclature NACRES :
NA.77

Niveau de qualité

Pureté

≥93% (HPLC)

Forme

powder

Solubilité

ethanol: 0.98-1.02 mg/mL, clear, colorless to faintly yellow

Conditions d'expédition

ambient

Température de stockage

room temp

Chaîne SMILES 

CC12CCC3C(CCc4cc(O)ccc34)C1CC(O)C2O

InChI

1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3

Clé InChI

PROQIPRRNZUXQM-UHFFFAOYSA-N

Actions biochimiques/physiologiques

16-Epiestriol is found naturally in various animals, plants, and fungal yeast. It potentially inhibits the growth of colistins and carbapenem-resistant A. baumannii
16-Epiestriol, an estradiol metabolite, possesses anti-inflammatory properties but no glycogenic properties.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Xia Xu et al.
Genome medicine, 4(4), 31-31 (2012-05-02)
Endogenous estrogens and estrogen metabolites play an important role in the pathogenesis and development of human breast, endometrial, and ovarian cancers. Increasing evidence also supports their involvement in the development of certain lung, colon and prostate cancers. In this study
Roni T Falk et al.
Breast cancer research : BCR, 15(2), R34-R34 (2013-04-24)
Elevated levels of circulating estrogens are linked to breast cancer risk among postmenopausal women but little is known about the importance of estrogen metabolism. A recently developed liquid chromatography tandem mass spectrometry-based method (LC-MS/MS) measuring a panel of 15 estrogen
Cher M Dallal et al.
Medicine and science in sports and exercise, 48(3), 439-448 (2015-10-16)
Physical activity may reduce endogenous estrogens, but few studies have assessed effects on estrogen metabolism and none have evaluated sedentary behavior in relation to estrogen metabolism. We assessed relationships between accelerometer-measured physical activity and sedentary behavior and 15 urinary estrogens
Sally B Coburn et al.
Cancer causes & control : CCC, 30(1), 75-86 (2018-12-07)
The comparability between serum, plasma, and urinary measurements of estrogen metabolites via liquid chromatography-tandem mass spectrometry (LC-MS/MS) has not been largely explored, and it is unclear if urinary LC-MS/MS measurements are suitable surrogates of circulating levels. Serum, plasma (EDTA and
Jodie M Fleming et al.
BMC medicine, 8, 27-27 (2010-05-25)
Breast cancer studies frequently focus on the role of the tumor microenvironment in the promotion of cancer; however, the influence of the normal breast microenvironment on cancer cells remains relatively unknown. To investigate the role of the normal breast microenvironment

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