AB1834P
Anti-Monocyte Chemotactic Protein-1 Antibody
Chemicon®, from rabbit
Synonyme(s) :
MCP-1, MCAF, CCL2
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
rabbit
Niveau de qualité
Forme d'anticorps
affinity purified immunoglobulin
Type de produit anticorps
primary antibodies
Clone
polyclonal
Produit purifié par
affinity chromatography
Espèces réactives
rat
Fabricant/nom de marque
Chemicon®
Technique(s)
ELISA: suitable
neutralization: suitable
western blot: suitable
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... CCL2(6347)
Spécificité
Reacts with rat MCP-1
Immunogène
Highly pure (>98%) recombinant rat MCP-1
Application
Anti-Monocyte Chemotactic Protein-1 Antibody is an antibody against Monocyte Chemotactic Protein-1 for use in ELISA, WB, NEUT.
ELISA: To detect rat MCP-1 (MCAF) by direct ELISA (using 100 μL/well antibody solution) a concentration of at lease 0.5 μg/mL of this antibody is required. Should allow detection of 0.2 - 0.4 ng/well of recombinant rat MCP-1 (MCAF).
Western blot: 0.1 - 0.2 μg/mL, this dilution should offer a detection limit of 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of rat MCP-1 (100 ng/mL), a concentration of 4.0-6.0 μg/mL of this antibody is required.
Optimal working dilutions must be determined by the end user.
Western blot: 0.1 - 0.2 μg/mL, this dilution should offer a detection limit of 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of rat MCP-1 (100 ng/mL), a concentration of 4.0-6.0 μg/mL of this antibody is required.
Optimal working dilutions must be determined by the end user.
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors
Cytokines & Cytokine Receptors
Forme physique
Affinity purified immunoglobulin. Lyophilized from 0.5X PBS pH 7.4. Contains no preservative. Reconstitute with sterile distilled water to 0.1 - 1.0 mg/ml.
Stockage et stabilité
Maintain lyophilized material desiccated at 2°-8°:C for up to 12 months from date of receipt. After reconstitution maintain at -20°C in convenient undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Autres remarques
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informations légales
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
13 - Non Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Fibrogenesis in pediatric cholestatic liver disease: role of taurocholate and hepatocyte-derived monocyte chemotaxis protein-1 in hepatic stellate cell recruitment.
Grant A Ramm, Ross W Shepherd, Anita C Hoskins, Sonia A Greco, Agnieszka D Ney et al.
Hepatology null
Regulated expression of matrix metalloproteinases, inflammatory mediators, and endometrial matrix remodeling by 17beta-estradiol in the immature rat uterus.
Russo, LA; Peano, BJ; Trivedi, SP; Cavalcanto, TD; Olenchock, BA; Caruso, JA; Smolock et al.
Reproductive Biology and Endocrinology null
Clémence Guiraut et al.
International journal of molecular sciences, 17(12) (2016-11-30)
The medium-size intra-cranial arteries arising from the carotid bifurcation are prone to perinatal arterial ischemic strokes (PAIS). PAIS' physiopathology needs to be better understood to develop preventive and therapeutic interventions that are currently missing. We hypothesized that materno-fetal inflammation leads
Marie-Elsa Brochu et al.
Journal of neuroinflammation, 8, 55-55 (2011-05-24)
Preterm and term newborns are at high risk of brain damage as well as subsequent cerebral palsy and learning disabilities. Indeed, hypoxia-ischemia (HI), pathogen exposures, and associated intracerebral increase of pro-inflammatory cytokines have all been linked to perinatal brain damage.
Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation.
Reddy JP, Peddibhotla S, Bu W, Zhao J, Haricharan S, Du YC, Podsypanina K, Rosen JM et al.
Proceedings of the National Academy of Sciences of the USA null
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