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764892

Sigma-Aldrich

Polyethylenimine hydrochloride

linear, average Mn 4,000, PDI ≤1.3

Synonym(s):

Linear PEI HCl salt, Poly(ethylene imine hydrochloride), Poly(ethylene imine) HCl salt

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About This Item

Linear Formula:
CH3(NHC2H4)nOH·xHCl
UNSPSC Code:
12162002
NACRES:
NA.23

Quality Level

100

form

solid

mol wt

average Mn 4,000

mp

273-278 °C (decomposition)

PDI

≤1.3

storage temp.

2-8°C

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCM7185
MKCJ2049
MKCC7807
MKBX1973V
MKBT9589V

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Articles

Delivery of Nucleic Acids Using Polymers

This review will focus on the sub-sector of drug delivery concerning the delivery of nucleic acids, with a particular focus on poly(ethyleneimine).

Functionalized PEI and Its Role in Gene Therapy

Gene therapy has become one of the most discussed techniques in biomedical research in recent years.

Recent Progress on Nonviral Delivery Carriers for CRISPR/Cas9 Systems

The CRISPR/Cas9 system has recently emerged as a highly specific, efficient, and versatile gene editing technology that can be utilized to build disease models and correct diseased genes. Safe and effective delivery vectors for the CRISPR/Cas9 system are in critical need to enable clinical development and future applications of CRISPR/Cas9 systems. Professor Yang Liu summarizes recent progress in nonviral nanoparticle approaches for CRISPR/Cas9 delivery.

Functional Polymers for Biomedical Applications

Wide range of functional polymers for biomedical applications have been synthesized and structurally characterized. Several classes of polymers including biodegradable polymers, hydrophilic & amphiphilic polymers, and stimuli responsive polymers have been prepared using controlled and directed functionalization via "living" polymerization such as RAFT, ionic and ring opening polymerization. Selected polymers have been studied for their structure-properties relationship. "

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