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764647

Sigma-Aldrich

Polyethylenimine hydrochloride

linear, average Mn 10,000, PDI ≤1.5

Synonym(s):

Linear PEI HCl salt, Poly(ethylene imine hydrochloride), Poly(ethylene imine) HCl salt

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About This Item

Linear Formula:
CH3(NHC2H4)nOH·xHCl
UNSPSC Code:
12162002
NACRES:
NA.23

Quality Level

100

form

solid

mol wt

average Mn 10,000

mp

276-280 °C (decomposition)

PDI

≤1.5

storage temp.

2-8°C

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Related Categories

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCD1250
MKCC6774
MKCB9864
MKBW0473V
MKBL5501

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Sunmin Jung et al.
Science signaling, 13(623) (2020-03-19)
The enzyme γ-secretase generates β-amyloid (Aβ) peptides by cleaving amyloid protein precursor (APP); the aggregation of these peptides is associated with Alzheimer's disease (AD). Despite the development of various γ-secretase regulators, their clinical use is limited by coincident disruption of
Do Hoon Kwon et al.
Autophagy, 13(1), 70-81 (2016-10-30)
Hosts utilize macroautophagy/autophagy to clear invading bacteria; however, bacteria have also developed a specific mechanism to survive by manipulating the host cell autophagy mechanism. One pathogen, Legionella pneumophila, can hinder host cell autophagy by using the specific effector protein RavZ
Colin Hutton et al.
Cancer cell, 39(9), 1227-1244 (2021-07-24)
Fibroblasts display extensive transcriptional heterogeneity, yet functional annotation and characterization of their heterocellular relationships remains incomplete. Using mass cytometry, we chart the stromal composition of 18 murine tissues and 5 spontaneous tumor models, with an emphasis on mesenchymal phenotypes. This

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The CRISPR/Cas9 system has recently emerged as a highly specific, efficient, and versatile gene editing technology that can be utilized to build disease models and correct diseased genes. Safe and effective delivery vectors for the CRISPR/Cas9 system are in critical need to enable clinical development and future applications of CRISPR/Cas9 systems. Professor Yang Liu summarizes recent progress in nonviral nanoparticle approaches for CRISPR/Cas9 delivery.

Functional Polymers for Biomedical Applications

Wide range of functional polymers for biomedical applications have been synthesized and structurally characterized. Several classes of polymers including biodegradable polymers, hydrophilic & amphiphilic polymers, and stimuli responsive polymers have been prepared using controlled and directed functionalization via "living" polymerization such as RAFT, ionic and ring opening polymerization. Selected polymers have been studied for their structure-properties relationship. "

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