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Documentos

1544508

USP

Piroxicam

Name: Piroxicam
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Sinónimos:

4-Hydroxy-2-methyl-3-(pyrid-2-yl-carbamoyl)-2H-1,2-benzothiazine 1,1-dioxide

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About This Item

Fórmula empírica (notación de Hill):

C₁₅H₁₃N₃O₄S

Número de CAS:

36322-90-4

Peso molecular:

331.35

Número MDL:

MFCD00057317

Código UNSPSC:

41116107

ID de la sustancia en PubChem:

329750878

NACRES:

NA.24

grado

pharmaceutical primary standard

familia API

piroxicam

fabricante / nombre comercial

USP

aplicaciones

pharmaceutical (small molecule)

formato

neat

cadena SMILES

CN1C(C(=O)Nc2ccccn2)=C(O)c3ccccc3S1(=O)=O

InChI

1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20)

Clave InChI

QYSPLQLAKJAUJT-UHFFFAOYSA-N

Información sobre el gen

human ... PTGS1(5742) , PTGS2(5743)

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Piroxicam USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Piroxicam Capsules
Piroxicam Compounded Cream
Piroxicam Compounded Oral Suspension

Acciones bioquímicas o fisiológicas

Cyclooxygenase inhibitor.

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Otras notas

Sales restrictions may apply.

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Referencia del producto

Descripción

Precios

1544541

1544574

1544600

1544520

1544519

2-Aminopyridine, United States Pharmacopeia (USP) Reference Standard

Pictogramas

GHS06,GHS08

Palabra de señalización

Danger

Frases de peligro

H301,H373

Consejos de prudencia

P260 - P264 - P270 - P301 + P310 - P314 - P405

Clasificaciones de peligro

Acute Tox. 3 Oral - STOT RE 2 Oral

Órganos de actuación

Gastrointestinal tract

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Piroxicam-beta-cyclodextrin in the treatment of acute pain of rheumatic disease.

J Y Reginster et al.

European journal of rheumatology and inflammation, 12(4), 38-46 (1993-01-01)

Analgesics continue to be the mainstay of therapy in osteoarthritis. Non-steroidal anti-inflammatory drugs (NSAIDs) play an important role, particularly where there is a significant inflammatory component to the osteoarthritis. Piroxicam-beta-cyclodextrin (PBC) is a new formulation in which piroxicam has been

Piroxicam and other cyclooxygenase inhibitors: potential for cancer chemoprevention.

D L Earnest et al.

Journal of cellular biochemistry. Supplement, 16I, 156-166 (1992-01-01)

Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID) widely used for treatment of inflammatory arthritis. Recent experimental and clinical studies suggest that piroxicam, as well as other NSAIDs, may be useful for chemoprevention of colon cancer. While there is less information

Piroxicam-β-cyclodextrin: a GI safer piroxicam.

C Scarpignato

Current medicinal chemistry, 20(19), 2415-2437 (2013-02-12)

Although NSAIDs are very effective drugs, their use is associated with a broad spectrum of adverse reactions in the liver, kidney, cardiovascular (CV) system, skin and gut. Gastrointestinal (GI) side effects are the most common and constitute a wide clinical

Effects of piroxicam-beta-cyclodextrin on the gastrointestinal tract.

S Warrington

European journal of rheumatology and inflammation, 12(4), 29-37 (1993-01-01)

Piroxicam-beta-cyclodextrin (PBC), a complex of piroxicam with beta-cyclodextrin, was developed with the aim of improving the hydrosolubility and bioavailability of piroxicam. The complex is more rapidly absorbed, with a consequent reduction in the time of contact of piroxicam with the

Piroxicam decreases postirradiation colonic neoplasia in the rat.

M G Northway et al.

Cancer, 66(11), 2300-2305 (1990-12-01)

This study evaluated the effects of the nonsteroidal antiinflammatory agent piroxicam on chronic radiation proctitis in the rat. Forty female Wistar rats received a 2250-cGy dose of irradiation to the distal 2 cm of the colon. Twenty received piroxicam 8.0

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