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Merck

PHR1588

Supelco

Piroxicam

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

Piroxicam, 4-Hydroxy-2-methyl-3-(pyrid-2-yl-carbamoyl)-2H-1,2-benzothiazine 1,1-dioxide

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About This Item

Fórmula empírica (notación de Hill):
C15H13N3O4S
Número de CAS:
Peso molecular:
331.35
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

certified reference material
pharmaceutical secondary standard

Nivel de calidad

Agency

traceable to Ph. Eur. P2130000
traceable to USP 1544508

familia API

piroxicam

CofA

current certificate can be downloaded

envase

pkg of 200 mg

técnicas

HPLC: suitable
gas chromatography (GC): suitable

aplicaciones

pharmaceutical (small molecule)

formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

CN1C(C(=O)Nc2ccccn2)=C(O)c3ccccc3S1(=O)=O

InChI

1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20)

Clave InChI

QYSPLQLAKJAUJT-UHFFFAOYSA-N

Información sobre el gen

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Descripción general

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Piroxicam belongs to the class of acidic, non-steroid anti-inflammatory (NSAI) drugs, with a long half-life which enables it to be administered once daily.

Aplicación

Piroxicam may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and urine by spectrophotometry.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Acciones bioquímicas o fisiológicas

Cyclooxygenase inhibitor.

Nota de análisis

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Otras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota al pie de página

To see an example of a Certificate of Analysis for this material enter LRAA4573 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Productos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictogramas

Skull and crossbonesHealth hazard

Palabra de señalización

Danger

Frases de peligro

Clasificaciones de peligro

Acute Tox. 3 Oral - STOT RE 2 Oral

Órganos de actuación

Gastrointestinal tract

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Certificados de análisis (COA)

Lot/Batch Number

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Visite la Librería de documentos

Sensitive spectrophotometric methods for the determination of amoxycillin, ciprofloxacin and piroxicam in pure and pharmaceutical formulations.
Nagaralli BS, et al.
Journal of Pharmaceutical and Biomedical Analysis, 29(5), 859-864 (2002)
Spectrophotometric determination of piroxicam and tenoxicam in pharmaceutical formulations using alizarin.
Amin AS
Journal of Pharmaceutical and Biomedical Analysis, 29(4), 729-736 (2002)
A simple spectrofluorimetric method for determination of piroxicam and propranolol in pharmaceutical preparations.
Tabrizi AB
Journal of food and drug analysis, 15(3) (2007)
Anal. Profiles Drug Subst., 15, 509-531 (1986)
Determination of piroxicam in pharmaceutical formulations and urine samples using europium-sensitized luminescence.
Al-Kindy SMZ, et al.
Journal of Luminescence, 127(2), 291-296 (2007)

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