T7189

Tumor Necrosis Factor Soluble Receptor II (TNF sRII)/Fc Chimera human

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture

• Número MDL: MFCD02689206
• Código UNSPSC: 51111800
• NACRES: NA.32

Propiedades

• origen biológico: human
• Nivel de calidad: 200
• recombinante: expressed in NSO cells
• Ensayo: >95% (SDS-PAGE)
• Formulario: lyophilized powder
• potencia: 0.004-0.016 mg per mL ED₅₀
• mol peso: 52.6 kDa
• envase: pkg of 50 μg
• condiciones de almacenamiento: avoid repeated freeze/thaw cycles
• técnicas: cell culture | mammalian: suitable
• impurezas: endotoxin, tested
• Nº de acceso UniProt: P20333
• temp. de almacenamiento: −20°C
• Información sobre el gen: human ... TNFRSF1B(7133)

Descripción

Aplicación

Tumor Necrosis Factor Soluble Receptor II (TNF sRII)/Fc Chimera human can be used as a test compound for analyzing the interaction between tumor necrosis factor (TNF) and its two soluble receptors by using surface plasmon resonance (SPR) technique.

Acciones bioquímicas o fisiológicas

Tumor Necrosis Factor Soluble Receptor II (TNF sRII)/Fc Chimera human belongs to TNF family of receptors and mediates the metabolic effects of TNF-α. Tumor Necrosis Factor Soluble Receptor II blocks the TNF-α-induced apoptosis and hence regulates the TNF-α function. It also has a pivotal role in neutralizing the biological activities of both TNF-α and TNF-β.

Forma física

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline

Nota de análisis

The biological activity is measured by its ability to neutralize the TNF-α mediated cytotoxicity in mouse L-929 cells in the presence of the metabolic inhibitor actinomycin D.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable