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Merck

T1539

Sigma-Aldrich

(+)-α-Tocopherol

Type VI, from vegetable oil, liquid (≥0.88M based on potency, density and molecular wt.), BioReagent, suitable for insect cell culture, ≥1000 IU/g

Sinónimos:

2,5,7,8-Tetramethyl-2-(4′,8′,12′-trimethyltridecyl)-6-chromanol, 5,7,8-Trimethyltocol, D-α-Tocopherol, Vitamin E

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About This Item

Fórmula empírica (notación de Hill):
C29H50O2
Número de CAS:
Peso molecular:
430.71
Beilstein:
4712525
Número CE:
Número MDL:
Código UNSPSC:
12352205
eCl@ss:
34058016
ID de la sustancia en PubChem:
NACRES:
NA.75

origen biológico

vegetable oil

tpo

Type VI

Línea del producto

BioReagent

formulario

liquid (≥0.88M based on potency, density and molecular wt.)

potencia

≥600 mg d-α-tocopherol per g

actividad específica

≥1000 IU/g

mol peso

Mw 430.71 g/mol

concentración

≥600 mg/g

técnicas

cell culture | insect: suitable

color

yellow-orange

índice de refracción

n20/D 1.505 (lit.)

bp

200-220 °C/0.1 mmHg (lit.)

solubilidad

chloroform: soluble 0.1 mL/mL, clear, faintly yellow to yellow

densidad

0.95 g/mL at 25 °C (lit.)

formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(O)c(C)c(C)c2O1

InChI

1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3/t21-,22-,29-/m1/s1

Clave InChI

GVJHHUAWPYXKBD-IEOSBIPESA-N

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Aplicación

Use in insect cell culture applications as an antioxidant.

Otras notas

Mixed constitutional (α, β, γ, δ) isomers.

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

230.0 °F - closed cup

Punto de inflamabilidad (°C)

110 °C - closed cup

Equipo de protección personal

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


Certificados de análisis (COA)

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Y Loetscher et al.
Poultry science, 92(11), 2938-2948 (2013-10-19)
Prevention of lipid oxidation needs special attention because a high proportion of fatty acids in broiler meat are unsaturated. A feeding experiment was conducted to evaluate the antioxidant effect of dietary addition of rosemary, chokeberry pomace, rosehip, or nettle in
Karl Michaëlsson et al.
The American journal of clinical nutrition, 99(1), 107-114 (2013-11-15)
A reduction in the formation of free radicals and oxidative stress might reduce the rate of bone loss and muscle wasting. The objective was to determine whether α-tocopherol intake or serum concentrations are associated with fracture risk in older women
Jen-Hao Cheng et al.
European journal of medicinal chemistry, 46(4), 1222-1231 (2011-02-25)
In an effort to develop novel antioxidant as anticancer agents, a series of xanthones were prepared. In vitro screening, the synthetic xanthones revealed significant inhibitory effects on xanthine oxidase and ABTS radical-cation scavenging activity. The selective compounds 2 and 8
Ying Yang et al.
Food chemistry, 141(1), 473-481 (2013-06-19)
Vitamin E is an essential micronutrient for humans and animals due to its antioxidant and non-antioxidant biological activities. The α-tocopherol acetate form is often used in foods and other products due to its high biological activity and chemical stability. In
Laura L Baxter et al.
Nutrients, 4(6), 467-490 (2012-07-24)
Vitamin E isoforms are essential nutrients that are widely used as dietary supplements and therapeutic agents for a variety of diseases. However, their pharmacokinetic (PK) properties remain poorly characterized, and high dosage animal studies may provide further information on their

Artículos

Importance and uses of vitamin E (tocopherol) in serum-free eukaryotic, including hybridoma and chinese hamster ovary (CHO), cell cultures.

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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