SRP8046

Netrin-1 (human): FC (human)

recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)

• Sinónimos: ACRP30headless:TNFSF13, NTN1
• Código UNSPSC: 12352200
• NACRES: NA.32

Propiedades

• origen biológico: human
• recombinante: expressed in HEK 293 cells
• Análisis: >95% (SDS-PAGE)
• formulario: lyophilized
• mol peso: ~90 kDa by SDS-PAGE
• envase: pkg of 10 μg
• condiciones de almacenamiento: avoid repeated freeze/thaw cycles
• impurezas: <0.1 EU/μg endotoxin, tested
• color: white
• Nº de acceso UniProt: O95631
• Condiciones de envío: wet ice
• temp. de almacenamiento: −20°C
• Información sobre el gen: human ... NTN1(9423)

Descripción

Descripción general

Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin 1 is also Involved in tumorigenesis by regulating apoptosis.

Forma física

Lyophilized from PBS with trehalose and Brij35.

Reconstitución

Reconstitute with 100 μL deionized water.

Otras notas

Human netrin-1 (aa 25-604) is fused at the C-terminus to the Fc portion of human IgG1.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable