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SAB4700666

Sigma-Aldrich

Monoclonal Anti-Cytokeratin (Pan-reactive) antibody produced in mouse

clone C-11, purified immunoglobulin, buffered aqueous solution

Sinónimos:

Mouse Anti-Cytokeratin, Pan-reactive Cytokeratin Detection

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

mouse

Nivel de calidad

conjugado

unconjugated

forma del anticuerpo

purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

C-11, monoclonal

Formulario

buffered aqueous solution

reactividad de especies

mammals

concentración

1 mg/mL

técnicas

flow cytometry: suitable

isotipo

IgG1

Condiciones de envío

wet ice

temp. de almacenamiento

2-8°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... KRT1(3848)

Descripción general

Cytokeratins also known as keratins are filament-forming proteins of epithelial cells. In humans, there are 54 cytokeratins. These proteins are divided in to two sub-categories such as acidic type I keratins and basic-to-neutral type II keratins.
The antibody C-11 reacts with Cytokeratin peptides 4, 5, 6, 8, 10, 13, 18. Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.

Inmunógeno

Keratin-enriched preparation from human epidermoid carcinoma cell line A431

Aplicación

Monoclonal Anti-Cytokeratin (Pan-reactive) antibody produced in mouse has been used in immunocytochemistry.
The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 0.5 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Acciones bioquímicas o fisiológicas

Cytokeratins play an essential role in normal tissue structure and function. It also facilitates the maintenance of cell mechanical integrity.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Cytokeratin expression, fibrillar organization, and subtle function in liver cells
Marceau N and Loranger A
Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire, 73, 619-625 (1995)
Evaluation of a simple method for storage of blood samples that enables isolation of circulating tumor cells 96 h after sample collection
Apostolou P
Journal of biological research (Thessalonike?, Greece) (2017)
New consensus nomenclature for mammalian keratins
Schweizer J
The Journal of Cell Biology, 174, 169-174 (2006)
Panagiotis Apostolou et al.
Journal of biological research (Thessalonike, Greece), 24, 11-11 (2017-10-05)
Minimizing the effects of transportation on the properties of biological material is a major challenge for the scientific community. The viability of cells is important in cases where their study is urgent for evaluation of treatment response or for the
Martine Broekema et al.
Kidney international, 68(6), 2572-2581 (2005-12-01)
Ischemia/reperfusion (I/R) injury is a major cause of acute renal failure (ARF). ARF is reversible, due to an innate regenerative process, which is thought to depend partly on bone marrow-derived progenitor cells. The significance of these cells in the repair

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