SAB4700059

Monoclonal Anti-CD4 , (N-terminal) antibody produced in mouse

clone MEM-241, purified immunoglobulin, buffered aqueous solution

• Sinónimos: Anti-CD4mut, Anti-IMD79, Anti-OKT4D
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• conjugado: unconjugated
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: MEM-241, monoclonal
• Formulario: buffered aqueous solution
• reactividad de especies: human
• concentración: 1 mg/mL
• técnicas: flow cytometry: suitable
• isotipo: IgG1
• Nº de acceso NCBI: NM_000616.4
• Nº de acceso UniProt: P01730
• Condiciones de envío: wet ice
• temp. de almacenamiento: 2-8°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... CD4(920)

Descripción

Descripción general

CD4 (cluster of differentiation 4) molecule is encoded by the gene mapped to human chromosome 12p13.31. The encoded protein is mainly localized on the surface of specific leukocytes. CD4 is characterized with a four ecto-domains (D1-D4) of which D1, D2 and D4 contain disulfide bonds.

Inmunógeno

2 N-terminal domains of human CD4 fused to human IgG1 Fc

Aplicación

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 1 μg/mL of sample of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Acciones bioquímicas o fisiológicas

CD4 (cluster of differentiation 4) facilitates the activation of immunostimulatory T-cells. It serves as a primary receptor for HIV-1 entry. The encoded protein also plays a key role in altering cell elasticity. Elevated expression of soluble CD4 has been observed in patients of infectious and chronic inflammatory diseases and rheumatoid arthritis (RA). Thus, this protein can be used as a potential diagnostic marker for the development of RA.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forma física

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable