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Merck
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SAB4300102

Sigma-Aldrich

Anti-phospho-AKT2 (pSer474) antibody produced in rabbit

affinity isolated antibody

Sinónimos:

Anti-PKBB antibody produced in rabbit, Anti-PKBBETA antibody produced in rabbit, Anti-PRKBB antibody produced in rabbit, Anti-RAC-BETA antibody produced in rabbit, Anti-v-akt murine thymoma viral oncogene homolog 2 antibody produced in rabbit

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About This Item

Número MDL:
MFCD01633020
Código UNSPSC:
12352203
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

100

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

Formulario

buffered aqueous solution

mol peso

~60 kDa

reactividad de especies

human, rat, mouse

concentración

1 mg/mL

técnicas

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
western blot: 1:500-1:1000

isotipo

IgG

secuencia del inmunógeno

(Q-F-SP-Y-S)

Nº de acceso NCBI

NP_001617.1

Nº de acceso UniProt

P31751

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

phosphorylation (pSer474)

Información sobre el gen

human ... AKT2(208)

Inmunógeno

Peptide sequence around phosphorylation site of serine 474 (Q-F-S(p)-Y-S), according to the protein AKT2.

Características y beneficios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Descripción de destino

General protein kinase capable of phosphorylating several known proteins.

Forma física

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
871511124

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Jinlong Zhao et al.
International journal of medical sciences, 15(10), 1062-1071 (2018-07-18)
Rac1, known as a "molecular switch", plays a crucial role in plenty of cellular processes. Rac1 aggravates the damage of myocardial cells in the process of myocardial ischemia-reperfusion during myocardial infarction through activating the NADPH oxidase and bringing about the
Victoria H Cruz et al.
Molecular metabolism, 16, 139-149 (2018-06-25)
TANK Binding Kinase 1 (TBK1) has been implicated in the regulation of metabolism through studies with the drug amlexanox, an inhibitor of the IκB kinase (IKK)-related kinases. Amlexanox induced weight loss, reduced fatty liver and insulin resistance in high fat
Zhenbing Lv et al.
Journal of translational medicine, 15(1), 257-257 (2017-12-21)
Metastasis is a major threat to colorectal cancer (CRC) patients. We have reported that peroxiredoxin-2 (PRDX2) is associated with CRC invasion and metastasis. However, the mechanisms regulating PRDX2 expression remain unclear. We investigate whether microRNAs (miRNAs) regulate PRDX2 expression in
Alberto Bavelloni et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(8), 9044-9061 (2019-05-17)
Murine thymoma viral oncogene homolog (AKT) kinases target both cytosolic and nuclear substrates for phosphorylation. Whereas the cytosolic substrates are known to be closely associated with the regulation of apoptosis and autophagy or metabolism and protein synthesis, the nuclear substrates
K Soukupová et al.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 52, 58-67 (2019-02-09)
The specific effects of sodium selenite (selenite) on a chemoresistant human bladder cancer cell line RT-112/D21 were investigated during 72 h. Selenite at low concentration of 2.5 μmol (otherwise tolerated in normal urothelial cells UROtsa) suppressed growth and proliferation of the tested
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