SAB1300534

Anti-SHB (N-term) antibody produced in rabbit

saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution

• Sinónimos: Anti-SH2 domain-containing adapter protein B
• Código UNSPSC: 12352203
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 200
• conjugado: unconjugated
• forma del anticuerpo: saturated ammonium sulfate (SAS) precipitated
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• formulario: buffered aqueous solution
• reactividad de especies: human
• técnicas: immunohistochemistry: 1:50-1:100; indirect ELISA: 1:1000
• Nº de acceso NCBI: NP_003019
• Nº de acceso UniProt: Q15464
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... SHB(6461)

Descripción

Descripción general

SHB is an adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. It may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. It may also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades, and may also regulate IRS1 and IRS2 signaling in insulin-producing cells.

Inmunógeno

SHB (NP_003019, 15-49)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-term region of human SHB.

Forma física

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): nwg
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable