S8251

Succinylcholine chloride dihydrate

98.0-102.0%, solid

• Sinónimos: Bis(trimethylammonioethyl) succinate chloride, Succinyldicholine dichloride
• Fórmula lineal: [(CH₃)₃NCH₂CH₂OCOCH₂]₂Cl₂ · 2H₂O
• Número de CAS: 6101-15-1
• Peso molecular: 397.34
• Beilstein: 3922827
• Número CE: 200-747-4
• Número MDL: MFCD00150564
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 24277873
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Ensayo: 98.0-102.0%
• Formulario: solid
• color: white
• solubilidad: H₂O: complete 100 mg/ml, clear to slightly hazy, colorless; H₂O: soluble (unstable at pH > 9.)
• emisor: Novartis
• cadena SMILES: O.O.[Cl-].[Cl-].C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C
• InChI: 1S/C14H30N2O4.2ClH.2H2O/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;;;/h7-12H2,1-6H3;2*1H;2*1H2/q+2;;;;/p-2
• Clave InChI: FFSBEIRFVXGRPR-UHFFFAOYSA-L

Descripción

Aplicación

Succinylcholine chloride dehydrate was used to study the mechanism of gating of Cys loop receptors in Xenopus laevis.^4,5

Acciones bioquímicas o fisiológicas

Cholinergic antagonist which induces a long-lasting depolarization of the acetylcholine neuron membrane; neuromuscular blocking agent.

Succinylcholine is a cholinergic antagonist and a neuromuscular blocking agent. It induces depolarization of acetylcholine receptors on the muscle membrane and efflux of potassium from the muscle that leads to hypokalemia in individuals with upregulated expression of acetylcholine receptors.³

Características y beneficios

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Reconstitución

Solutions may be stored for several days at 4 °C.

Información de seguridad

• Pictogramas: GHS06
• Palabra de señalización: Danger
• Frases de peligro: H301
• Consejos de prudencia: P301 + P310
• Clasificaciones de peligro: Acute Tox. 3 Oral
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)