P7556

Progesterone-Water Soluble

powder, BioReagent, suitable for cell culture

• Sinónimos: Progesterone: HBC complex, Progesterone: methyl-β-cyclodextrin complex
• Número MDL: MFCD00003658
• Código UNSPSC: 12352209
• ID de la sustancia en PubChem: 57654558
• NACRES: NA.77

Propiedades

• origen biológico: synthetic (organic)
• Nivel de calidad: 200
• Línea del producto: BioReagent
• formulario: powder
• concentración: ≥65% (HPLC)
• técnicas: cell culture | mammalian: suitable
• solubilidad: H₂O: 25 mg/mL, clear to slightly hazy
• Condiciones de envío: ambient
• temp. de almacenamiento: room temp
• cadena SMILES: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])C(C)=O
• InChI: 1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
• Clave InChI: RJKFOVLPORLFTN-LEKSSAKUSA-N
• Información sobre el gen: human ... ABCB1(5243) , AR(367) , CYP2C9(1559) , EBP(10682) , ESR1(2099) , ESR2(2100) , NR3C1(2908) , NR3C2(4306) , PGR(5241) , SERPINA6(866) ; mouse ... Esr1(13982) ; rat ... Ar(24208) , Nr3c1(24413) , Pgr(25154)

Descripción

Descripción general

Progesterone is a steroid hormone secreted by the ovaries.

Aplicación

Progesterone-Water Soluble has been used:

• for in vitro maturation of oocyte complexes
• as a σ1R antagonist to study its effect on sigma 1 receptor
• to study its effect on the differentiation of human multipotent mesenchymal stromal cells (hMSCs) in vitro

This product is not recommended for use in binding assays.

Acciones bioquímicas o fisiológicas

Progesterone is a hormone that maintains pregnancy. It is essential for embryo formation, development and survival in almost all mammals. This hormone exhibits its action via progesterone receptor, which is specifically expressed in the endometrial stroma throughout pregnancy. It is known to prevent preterm delivery, when administered intramuscularly. Progesterone also controls gonadotropin secretion, activates sexual behavior and triggers ovarian events leading to ovulation. It stimulates the growth and differentiation of the uterus and prevents uterine contractility.

Envase

Package size based on progesterone content

Otras notas

Contains approx. 70 mg progesterone per gram; balance methyl-β-cyclodextrin.

Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Danger
• Frases de peligro: H351,H360FD,H362
• Consejos de prudencia: P202 - P260 - P263 - P264 - P280 - P308 + P313
• Clasificaciones de peligro: Carc. 2 - Lact. - Repr. 1A
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable