N1638

Nystatin Suspension

suspension, non-animal origin, suitable for cell culture, BioReagent

• Sinónimos: Fungicidin, Mycostatin
• Número de CAS: 1400-61-9
• Código UNSPSC: 12352207
• ID de la sustancia en PubChem: 24897511
• NACRES: NA.76

Propiedades

• Nombre del producto: Nystatin Suspension, suspension, 10,000 unit/mL in DPBS, BioReagent, suitable for cell culture
• Línea del producto: BioReagent
• Nivel de calidad: 200
• Formulario: suspension
• concentración: 10,000 unit/mL in DPBS
• técnicas: cell culture | mammalian: suitable
• impurezas: endotoxin, tested
• color: yellow
• espectro de actividad antibiótica: fungi; yeast
• Modo de acción: cell membrane | interferes
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• cadena SMILES: C[C@@H]1OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@]2(O)C[C@H](O)[C@H]([C@H](C[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)\C=C\C=C\C=C\C=C\CC\C=C\C=C\[C@H](C)[C@@H](O)[C@@H]1C)O2)C(O)=O
• InChI: 1S/C47H75NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-36(53)35(52)20-19-31(49)21-32(50)22-33(51)23-39(55)62-29(3)28(2)42(27)56/h5-6,8,10-18,27-38,40-44,46,49-54,56-58,61H,7,9,19-26,48H2,1-4H3,(H,59,60)/b6-5+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28+,29-,30+,31+,32+,33+,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1
• Clave InChI: VQOXZBDYSJBXMA-QEKUPDCNSA-N

Descripción

Descripción general

Chemical structure: polyene

Aplicación

Nystatin suspension has been used:

• to inhibit caveolin-mediated endocytosis
• as a component of Eagle′s minimum essential medium (EMEM)
• to enumerate lactic acid bacteria (LAB)
• in preventing cell culture contamination and inducing interleukin (IL)-1, IL-8, and tumor necrosis factor a secretion in toll-like receptor 2 (TLR2)-expressing THP1 cells.

This product is recommended for use in cell culture applications at 24 mL/L.

Acciones bioquímicas o fisiológicas

Nystatin is a polyene, broad-spectrum antibiotic, which modifies the microstructure of lipid rafts. It can sequester cholesterol present on the cell membrane of eukaryotes. Nystatin regulates immune responses through cytokine signaling, lymphocyte activation and pathogen recognition.

Precaución

This product is stable at 37°C for three days.

Nota de preparación

It is 0.1μ filtered and cell culture tested.

Otras notas

Nystatin suspension available in 20 mL and 100 mL pack size.
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable