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M1890

Sigma-Aldrich

rac-Glycerol 1-myristate

≥99%

Sinónimos:

1-Monotetradecanoyl-rac-glycerol, rac-1-Myristoylglycerol, DL-α-Myristin, Monomyristin

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About This Item

Fórmula lineal:
H3C(CH2)12COOCH2CH(OH)CH2OH
Número de CAS:
589-68-4
Peso molecular:
302.45
Beilstein:
1727502
Número MDL:
MFCD00046760
Código UNSPSC:
12352211
ID de la sustancia en PubChem:
24896704
NACRES:
NA.25

origen biológico

synthetic (organic)

Nivel de calidad

200

Análisis

≥99%

formulario

powder

grupo funcional

ester
hydroxyl

tipo de lípido

neutral glycerides

Condiciones de envío

ambient

temp. de almacenamiento

−20°C

cadena SMILES

CCCCCCCCCCCCCC(=O)OCC(O)CO

InChI

1S/C17H34O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-17(20)21-15-16(19)14-18/h16,18-19H,2-15H2,1H3

Clave InChI

DCBSHORRWZKAKO-UHFFFAOYSA-N

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Descripción general

rac-Glycerol 1-myristate is present in the saw palmetto palm and is less soluble in water.

Aplicación

rac-Glycerol 1-myristate has been used:
  • as a standard in liquid chromatography/atmospheric-pressure chemical ionization mass spectrometry (LC–APCI-MS) studies
  • as a representative monoacylglycerol to test its matrix effects in gas chromatography-mass spectrometry (GC-MS) studies
  • to test its antifungal activity against Fusarium spp.

Rac-glycerol 1-myristate (glycerol α-monomyristate) is used in colloidal chemistry as a nonionic surfactant in the development of micelles.

Acciones bioquímicas o fisiológicas

rac-Glycerol 1-myristate also elicits antifungal activity. It exhibits an anti-proliferative effect in HeLa cervical cancer cells when delivered as a polymeric nanoparticle-based conjugate.
rac-Glycerol 1-myristate, a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterial strains.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Hayami et al.
Journal of colloid and interface science, 220(2), 374-379 (1999-12-23)
The interfacial tension of a hexane solution of 1-monolaurin against water was measured as a function of temperature and concentration under atmospheric pressure. The thermodynamic quantity changes associated with the adsorption of 1-monolaurin were evaluated and compared with those of
Lok Kumar Shrestha et al.
The journal of physical chemistry. B, 113(18), 6290-6298 (2009-04-11)
In this paper we present the study of reverse micellar aggregates formed by glycerol alpha-monomyristate (C(14)G(1)) in different organic solvents. We have investigated the structure (mainly shape and size) of the monomyristin reverse micelles depending on alkyl chain length of
Wakako Tsuzuki
Lipids, 42(7), 613-619 (2007-06-22)
To elucidate the absorption characteristics of dietary lipids in the human intestine, we investigated the cellular uptake of lipid metabolites using a differential monolayer of the Caco2 cells. As lipid metabolites, several free fatty acids and 2-monoacylglycerols, were formed a
M Suman et al.
Journal of chromatography. A, 1216(18), 3758-3766 (2009-03-17)
A new, reliable liquid chromatography/atmospheric-pressure chemical ionisation mass spectrometry (LC-APCI-MS) method was developed for the quantitative determination of food emulsifiers composed of mono- and diacylglycerols of fatty acids (E471 series) in complex food matrices. These additives are extremely interesting for
Sirirat Boondireke et al.
Colloids and surfaces. B, Biointerfaces, 176, 9-17 (2018-12-28)
The cytotoxicity of monomyristin (MM), a monoacylglycerol, was investigated against cervical cancer cells (HeLa) and two normal cells (Vero and endometrial epithelial cells). MM exhibited cytotoxicity specifically to HeLa cells and not against normal cells except at the highest investigated
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