L6143
Lipopolysaccharides from Salmonella enterica serotype typhimurium
suitable for cell culture, BioXtra, γ-irradiated
Sinónimos:
LPS
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About This Item
Productos recomendados
origen biológico
Salmonella enterica (serotype typhimurium)
Nivel de calidad
esterilidad
γ-irradiated
Línea del producto
BioXtra
formulario
lyophilized powder
purificado por
gel-filtration chromatography
técnicas
cell culture | mammalian: suitable
impurezas
<1% Protein (Lowry)
temp. de almacenamiento
2-8°C
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Aplicación
Lipopolysaccharides from Salmonella enterica serotype typhimurium has been used:
- in mice to elicit the secretion of pro-inflammatory cytokines
- to induce cytokine production in monocytes
- to elicit the activation of NF-κB pathway in mouse dendritic cells.
- to induce inflammatory response in human colon adenocarcinoma Caco-2 cells
- for stimulation of the catfish peripheral blood leukocytes (PBLs) to study estrogen receptor mRNA expression
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).
Acciones bioquímicas o fisiológicas
LPS is a major constituent of the cell wall of most gram negative bacteria. It is a highly immunogenic antigen with the ability to enhance immune responses to soluble antigens. LPS also acts as a specific mitogen for bone marrow derived B lymphocytes from mice, rabbits, chickens, cows, hamsters, and humans.
Reconstitución
Lipopolysaccharides are supplied as lyophilized, γ-irradiated powders. To reconstitute, add 1 ml sterile balanced salt solution or tissue culture medium to the vial (1 mg) and gently swirl until the powder dissolves. Reconstituted product may be further diluted to desired working concentrations using sterile balanced salt solution or tissue culture medium.
Otras notas
To gain a comprehensive understanding of our extensive range of Lipopolysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Producto relacionado
Referencia del producto
Descripción
Precios
Palabra de señalización
Warning
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
Eyeshields, Gloves, type N95 (US)
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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